ID A0A1V3A1U1_9GAMM Unreviewed; 314 AA.
AC A0A1V3A1U1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Flap endonuclease {ECO:0000313|EMBL:OOC11296.1};
GN ORFNames=B1A74_01375 {ECO:0000313|EMBL:OOC11296.1};
OS Thioalkalivibrio halophilus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Thioalkalivibrio.
OX NCBI_TaxID=252474 {ECO:0000313|EMBL:OOC11296.1, ECO:0000313|Proteomes:UP000189177};
RN [1] {ECO:0000313|EMBL:OOC11296.1, ECO:0000313|Proteomes:UP000189177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HL17 {ECO:0000313|EMBL:OOC11296.1,
RC ECO:0000313|Proteomes:UP000189177};
RA Ahn A.-C., Meier-Kolthoff J., Overmars L., Richter M., Woyke T.,
RA Sorokin D.Y., Muyzer G.;
RT "Genomic diversity within the haloalkaliphilic genus Thioalkalivibrio.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OOC11296.1}.
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DR EMBL; MUZR01000004; OOC11296.1; -; Genomic_DNA.
DR RefSeq; WP_077243554.1; NZ_MUZR01000004.1.
DR AlphaFoldDB; A0A1V3A1U1; -.
DR STRING; 252474.B1A74_01375; -.
DR OrthoDB; 9806424at2; -.
DR Proteomes; UP000189177; Unassembled WGS sequence.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000313|EMBL:OOC11296.1};
KW Hydrolase {ECO:0000313|EMBL:OOC11296.1};
KW Nuclease {ECO:0000313|EMBL:OOC11296.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189177}.
FT DOMAIN 8..275
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 314 AA; 34435 MW; 40DB94B12910FBC8 CRC64;
MNACSDPAPC PTCTVVDTSI FVFRAWFARG LDPDPQGRPG GALHGFVHSL CQWLPRRAPG
PLGFCFDTSL RRGFRHRLDP GYKAHRPPAP PELRAQFERI GELLDALGLA RFSHPEYEAD
DLIATLTRNA RTAGLPVAVM SADKDLAQTI LGDRDHLHDP ERGRPMDRRA LEKRLRVRPD
QVADLLALAG DRSDNIPGIH GLGPRGAARI LRRLGDLESV LADPDAVRRC NLRRATALAQ
AIAADPERLR LSRRLTGLVD DVPGLPRGSD LPAELQPRGP VSDIHARLHD LGVHPDYHER
LLHVAAPTPE AIPA
//
