ID A0A1V3I8E5_9PAST Unreviewed; 531 AA.
AC A0A1V3I8E5;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=L-lactate permease {ECO:0000256|RuleBase:RU365092};
GN ORFNames=BKK48_08290 {ECO:0000313|EMBL:OOF35881.1};
OS Rodentibacter heidelbergensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Rodentibacter.
OX NCBI_TaxID=1908258 {ECO:0000313|EMBL:OOF35881.1, ECO:0000313|Proteomes:UP000189437};
RN [1] {ECO:0000313|EMBL:OOF35881.1, ECO:0000313|Proteomes:UP000189437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ac69 {ECO:0000313|EMBL:OOF35881.1,
RC ECO:0000313|Proteomes:UP000189437};
RA Christensen H.;
RT "Rodentibacter gen. nov. and new species.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Uptake of L-lactate across the membrane. Can also transport
CC D-lactate and glycolate. {ECO:0000256|RuleBase:RU365092}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU365092}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU365092}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the lactate permease family.
CC {ECO:0000256|ARBA:ARBA00010100, ECO:0000256|RuleBase:RU365092}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU365092}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OOF35881.1}.
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DR EMBL; MLHH01000022; OOF35881.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V3I8E5; -.
DR STRING; 1908258.BKK48_08290; -.
DR OrthoDB; 9761056at2; -.
DR Proteomes; UP000189437; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015129; F:lactate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR003804; Lactate_perm.
DR NCBIfam; TIGR00795; lctP; 1.
DR PANTHER; PTHR30003:SF0; GLYCOLATE PERMEASE GLCA; 1.
DR PANTHER; PTHR30003; L-LACTATE PERMEASE; 1.
DR Pfam; PF02652; Lactate_perm; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU365092};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365092};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU365092};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU365092};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365092}.
FT TRANSMEM 28..46
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 53..75
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 95..114
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 126..147
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 153..172
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 184..205
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 211..229
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 236..253
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 273..295
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 347..367
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 387..403
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 423..440
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 476..495
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
FT TRANSMEM 507..529
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365092"
SQ SEQUENCE 531 AA; 56434 MW; 68CFE2A90F11E3C5 CRC64;
MALFLSIFPI VLLIYLMVKR NALPSYLALP WIAVVVLIIQ LIFFGTDISI VSANIASALI
AVQTPITVIF GAILFNRFSE VSGATDILRK WLGNINPNPV AQIMIIGWAF AFMIEGASGF
GTPAAIAAPI LVGLGFPALR VAMLALVMNS VPVSFGAVGT PTWFGFGPLQ LAESQILEIG
SMTSLIHGFA ALVIPLMALS LIVSWSEIRK NLIFIYISIF ACVVPYMLLA QVNYEFPSLV
GGAIGLFVSV IVANKGIGLA KVEKTLEGSS VSLAQVAKAL FPTGMLIAIL IVTRIQQLPF
KAMMNNATSW FSTQLGSLGL FDVSHGLIFS LKNIFGTSIN ASYKLLYVPA FIPFVVTVLI
AVPVFALSMS KTKDIFVTSL KQTKNPFFAL VGALVMVNLM LVGGDNSMVK IIGQSFAHAT
GEYWTLFASY LGAVGAFFSG SNTVSNLTFG SVQLSTAELT GLSASLILAL QSVGGAMGNM
VCINNIVAVS SVLNIDKQEG TIIKKTVVPM IVYGIIAALV ALFIIPIFYA V
//
