ID A0A1V3NF52_9GAMM Unreviewed; 876 AA.
AC A0A1V3NF52;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=B1C78_10410 {ECO:0000313|EMBL:OOG23690.1};
OS Thioalkalivibrio denitrificans.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Thioalkalivibrio.
OX NCBI_TaxID=108003 {ECO:0000313|EMBL:OOG23690.1, ECO:0000313|Proteomes:UP000189462};
RN [1] {ECO:0000313|EMBL:OOG23690.1, ECO:0000313|Proteomes:UP000189462}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ALJD {ECO:0000313|EMBL:OOG23690.1,
RC ECO:0000313|Proteomes:UP000189462};
RA Ahn A.-C., Meier-Kolthoff J., Overmars L., Richter M., Woyke T.,
RA Sorokin D.Y., Muyzer G.;
RT "Genomic diversity within the haloalkaliphilic genus Thioalkalivibrio.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OOG23690.1}.
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DR EMBL; MVBK01000059; OOG23690.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V3NF52; -.
DR STRING; 108003.B1C78_10410; -.
DR OrthoDB; 1931120at2; -.
DR Proteomes; UP000189462; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd18161; REC_hyHK_blue-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000189462};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..876
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012053276"
FT TRANSMEM 161..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 188..240
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 245..318
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 319..371
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 512..735
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 756..872
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 228..255
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 806
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 876 AA; 97412 MW; 8ED8E0436B135522 CRC64;
MKLRTLSGTF LTAALAALLL LGAFSVHAWR TFSGHLEDIH TFSELRTEME QFKSAIDYVT
LIRSDIDVLQ GVGVDARRLA ESIRTLDPVA GAPAILHLNE IAHLSEVLAE AAPDTSLLHA
DELQRDTLMA LSRQLLVHRS GVTDVLNTLD RAQDESVATA LMALVGTLTA VAMALALLSL
IGFTLIHRRL RRPLADLQRG LSLFARGDPD THIPIRGNDE LGELARLFNR MVDQRQQYED
TLKDQEERFR QLAENIDEVF WMSTPDKRSV LYVSPAFERV WGVSCGALYD RPEVWLDAIH
EEDRARVIEA AGRQAKGTYN EEYRVVRPDG SVRMILDRAF PIHDDRGQVY RIAGVAVDVT
HMRQMEVDLR ERVKELRTLY RILELTADAT RTTYEVCEEV ANMLPAGFTW PEHAVARVVI
GSEEWRSPCW ETPTFKIMST IRHDGTDEGF IEVGYTRLPA EAQPQSDPFL PEEQPLLDGV
AGHLSRMLHT RRMIHTLNQS DRLSAIGQLT GGVAHDFNNL LTVIIGNAEL LQLRMDRDDT
LRGLVDMIGS AAQRGAELTQ RLLAFSRHQV LEPRIIDANA HLEGITDLLQ RALGEHIEIR
FVLTPDLWPA MVDPGQLENA LLNLCINARD AMGDGGFLTI ETANAVLDEH YADTHMEVNP
GEYVLLSVTD TGEGIAPEIL DKVFEPFFTT KGAERGTGLG LSMVHGFVKQ SGGQISIYSE
PGHGTTVRLY LPRAAHTDMK DAAATTDAGT RRGDEIILLV EDDRLVRRYA QEQLSALGYT
VLVATNAHEA LGVLHEHLNV DLLFTDVVMP GGMNGRELAD AARALHPDIR VLYTSGYTQN
AIVHQGRLDT GVLLLAKPYR QADLARKVRE ALDGPR
//
