ID A0A1V3P0J6_9GAMM Unreviewed; 1061 AA.
AC A0A1V3P0J6;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Efflux pump membrane transporter {ECO:0000256|RuleBase:RU364070};
GN ORFNames=B0E52_13575 {ECO:0000313|EMBL:OOG38849.1};
OS Rhodanobacter sp. C06.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Rhodanobacteraceae; Rhodanobacter.
OX NCBI_TaxID=1945854 {ECO:0000313|EMBL:OOG38849.1, ECO:0000313|Proteomes:UP000189228};
RN [1] {ECO:0000313|EMBL:OOG38849.1, ECO:0000313|Proteomes:UP000189228}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C06 {ECO:0000313|EMBL:OOG38849.1,
RC ECO:0000313|Proteomes:UP000189228};
RA Lycus P., Bothun K.L., Bergaust L., Shapleigh J.P., Bakken L.R.,
RA Frostegard A.;
RT "Phenotypic and genotypic richness of denitrifiers revealed by a novel
RT isolation strategy.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU364070}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU364070}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942,
CC ECO:0000256|RuleBase:RU364070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OOG38849.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MUNP01000062; OOG38849.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V3P0J6; -.
DR STRING; 1945854.B0E52_13575; -.
DR OrthoDB; 9757904at2; -.
DR Proteomes; UP000189228; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042908; P:xenobiotic transport; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004764; MdtF-like.
DR InterPro; IPR000731; SSD.
DR NCBIfam; TIGR00915; 2A0602; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF11; EFFLUX PUMP MEMBRANE TRANSPORTER; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU364070};
KW Cell membrane {ECO:0000256|RuleBase:RU364070};
KW Membrane {ECO:0000256|RuleBase:RU364070};
KW Reference proteome {ECO:0000313|Proteomes:UP000189228};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364070};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364070}; Transport {ECO:0000256|RuleBase:RU364070}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 343..363
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 370..390
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 396..420
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 441..461
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 473..500
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 549..568
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 882..901
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 908..928
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 934..957
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 978..998
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 1010..1037
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT DOMAIN 369..498
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 1061 AA; 114791 MW; 602097D558B3F4F3 CRC64;
MKNIAQFFVD RPIMAAVLSL LFVITGSIAV FQLPISEYPE VVPPTVVVRA NYPGANPKVI
AETVATPLET QINGVEGMLY TSSQATSDGV MTLTVTFALG TNLNDAQVEV QNRVSQALPR
LPEEVQRLGV TTQKSSPDLT MVVHLTSPDK RYDMLYLSNF ARLHVKDVLG RLNGVGDVQI
FGAGEYSMRV WLNPDKLAQR GLTTGDVANA IREQNVQVAA GALNAPPVRG TADFQLNINT
QGRLSTVDDF RNIVLRTDAD GATVHLGDVA RVELGSNQYA LRSLLDNQPA VAIPIFARPG
SNAIQISDEV RATMAQLKKE FPQGIDYHIV YDPTVFVRGS IEAVAHTLLE AILLVVLVVI
LFLQTWRASV IPLIAVPVSL IGTFAVMYLV GFSLNALSLF GMVLAIGIVV DDAIVVVENV
ERHIELGQSP KEATRKAMHE VTGPIVATAL VLCAVFIPTA FISGLTGEFY RQFALTIAIS
TVISAFNSLT LSPALSAILL KPHGAPKDRL TRAIDRLFGW LFRPFNRLFQ RGAERYVAGT
RRMQGKGGAA LLVYAGLIAL TAFGFWHVPT GFVPTQDKQY LVSFAQLPDA ASLDRTEDVI
KQMSAIALKQ PGVQSAVAFP GLSVNGFTNS TNAGIVFVTL KPFEERRSAD LSAGAIAGAL
NAKFAAIQDA YIAVFPPPPV MGLGTIGGFR LQIEDRGQVG FDELYQQTQK LIAASRKDPV
LAGLFSSFQV NVPQVDVNVD REKAKAEGVN LGDVYQTMQA YLGSLYVNDF NRFGRTYQVN
LSAEPQFRSD LEDISQLKTR NAKGEMVPLG SFVTVAHGAG PDRVQHYNGY PTAEINGGPA
PGYSSGQAQA EIEKLAREVL PNGMSYEWTD LTYQQILAGN TAVLVFPLCV LLVFLVLSSL
YESWSLPLAV ILIVPMVLLS AIAGVWLSGG DNNIFTQIGL IVLVGLACKN AILIVEFARE
RQLEGMSRHE AVLEAARLRL RPILMTSIAF IMGVVPLVTS HGAGAEMRHA MGVAVFSGML
GVTLFGLLYT PLFYVVIRAL VERREARKHA QANALPALEG H
//
