ID   A0A1V4A121_9ACTN        Unreviewed;       342 AA.
AC   A0A1V4A121;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Histidinol phosphatase {ECO:0000313|EMBL:OON72191.1};
GN   ORFNames=B1H18_30825 {ECO:0000313|EMBL:OON72191.1};
OS   Streptomyces tsukubensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=83656 {ECO:0000313|EMBL:OON72191.1, ECO:0000313|Proteomes:UP000190539};
RN   [1] {ECO:0000313|EMBL:OON72191.1, ECO:0000313|Proteomes:UP000190539}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F601 {ECO:0000313|EMBL:OON72191.1,
RC   ECO:0000313|Proteomes:UP000190539};
RA   Zong G., Zhong C., Fu J., Qin R., Cao G.;
RT   "Draft Genome Sequence of Streptomyces tsukubaensis F601, a Producer of the
RT   immunosuppressant tacrolimus FK506.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OON72191.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MVFC01000041; OON72191.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V4A121; -.
DR   STRING; 83656.B1H18_30825; -.
DR   Proteomes; UP000190539; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd07436; PHP_PolX; 1.
DR   Gene3D; 1.10.150.110; DNA polymerase beta, N-terminal domain-like; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR010996; DNA_pol_b-like_N.
DR   InterPro; IPR027421; DNA_pol_lamdba_lyase_dom_sf.
DR   InterPro; IPR004013; PHP_dom.
DR   InterPro; IPR003141; Pol/His_phosphatase_N.
DR   InterPro; IPR016195; Pol/histidinol_Pase-like.
DR   InterPro; IPR047967; PolX_PHP.
DR   InterPro; IPR017078; UCP036978_PHPhdr.
DR   PANTHER; PTHR36928; PHOSPHATASE YCDX-RELATED; 1.
DR   PANTHER; PTHR36928:SF1; PHOSPHATASE YCDX-RELATED; 1.
DR   Pfam; PF14716; HHH_8; 1.
DR   Pfam; PF02811; PHP; 1.
DR   PIRSF; PIRSF036978; UCP036978_PHPhdr; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   SUPFAM; SSF47802; DNA polymerase beta, N-terminal domain-like; 1.
DR   SUPFAM; SSF89550; PHP domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000190539}.
FT   DOMAIN          101..180
FT                   /note="Polymerase/histidinol phosphatase N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00481"
SQ   SEQUENCE   342 AA;  36678 MW;  33D918F00702167F CRC64;
     MEPVTALDRI AFLLERAQAP VYRVRAFRGA SAAVAALGGE ETRRRAADSE LEQLKGVGPK
     TAQVVREALA GTTPAYLARL EDDSRGPVTT GGERLRALLR GDCHLHSDWS DGGSAIEEMG
     EAAAALGHEW AALTDHSPRL TVAHGLSAER LREQLSVVAA LNERWAPFRL LTGIECDILA
     DGTLDQDPGL LDRLDVVVAS VHSKLRMDAA EMTRRMIAAV RDPHTDILGH CTGRLVTGRG
     RPESRFDAEA VFAACAESGT AVEINSRPER LDPPRRLLRP AVAAGTLFAV DTDAHAPGQL
     DWQPYGCARA EECGVPPERV VNTWGAERLL EWTGASSGPS GP
//