ID   A0A1V4A982_9ACTN        Unreviewed;       457 AA.
AC   A0A1V4A982;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Cyclase {ECO:0000313|EMBL:OON79225.1};
GN   ORFNames=B1H18_14820 {ECO:0000313|EMBL:OON79225.1};
OS   Streptomyces tsukubensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=83656 {ECO:0000313|EMBL:OON79225.1, ECO:0000313|Proteomes:UP000190539};
RN   [1] {ECO:0000313|EMBL:OON79225.1, ECO:0000313|Proteomes:UP000190539}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F601 {ECO:0000313|EMBL:OON79225.1,
RC   ECO:0000313|Proteomes:UP000190539};
RA   Zong G., Zhong C., Fu J., Qin R., Cao G.;
RT   "Draft Genome Sequence of Streptomyces tsukubaensis F601, a Producer of the
RT   immunosuppressant tacrolimus FK506.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OON79225.1}.
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DR   EMBL; MVFC01000010; OON79225.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V4A982; -.
DR   STRING; 83656.B1H18_14820; -.
DR   OrthoDB; 3695445at2; -.
DR   Proteomes; UP000190539; Unassembled WGS sequence.
DR   CDD; cd07817; SRPBCC_8; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   InterPro; IPR005031; COQ10_START.
DR   InterPro; IPR047137; ORF3.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   PANTHER; PTHR33824; POLYKETIDE CYCLASE/DEHYDRASE AND LIPID TRANSPORT SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR33824:SF7; POLYKETIDE CYCLASE_DEHYDRASE AND LIPID TRANSPORT SUPERFAMILY PROTEIN; 1.
DR   Pfam; PF03364; Polyketide_cyc; 1.
DR   SUPFAM; SSF55961; Bet v1-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000190539}.
FT   DOMAIN          127..244
FT                   /note="Coenzyme Q-binding protein COQ10 START"
FT                   /evidence="ECO:0000259|Pfam:PF03364"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          45..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          273..457
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        283..389
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        390..410
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        411..441
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   457 AA;  51290 MW;  1D69E7323B2BDB22 CRC64;
     MAESGFSKIK DEVKNNPATD RLKEELQSYL QARAQKAVTG LGSKLGESVT KLANPSEGGG
     PGGLMSNLAK GGKALSEGKS PAQAAMSVGA SHMKDVVKDK VKGLFGKGRK GGGGKSKSVT
     IVEDIDVGVP VREAYDQWTQ FQEFSTFAKG VVSVEKSDDT SSNWKVKVAK STRSWKANVT
     EQVPDERITW TTEGAKGTVK GVVTFHRVTD NLTRVLMVLE YFPKGLFEKT GNIWRAQGRR
     ARLDLKLYRK FIMMRGEATD GWRGEIRDGE VVVEHDDAVA EEEEQKARDE EERESEDSDS
     EDSDSEDSED SEDSEAEGAE NDAEDDEYED DEESDEPRAE DDEAEYEDDE ELDEPRAEDD
     EAEYDEEDEP EEDSDEVRDE TDEDEESEDE DRTGRARSNG GRGRDKDDDD DKPRDEDEFR
     DDEDDEDEEY EDDEEPADEE EEPEHAPRRR RTAAARR
//