ID   A0A1V4AFP0_9ACTN        Unreviewed;       343 AA.
AC   A0A1V4AFP0;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Bile acid:sodium symporter {ECO:0000313|EMBL:OON82179.1};
GN   ORFNames=B1H18_03820 {ECO:0000313|EMBL:OON82179.1};
OS   Streptomyces tsukubensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=83656 {ECO:0000313|EMBL:OON82179.1, ECO:0000313|Proteomes:UP000190539};
RN   [1] {ECO:0000313|EMBL:OON82179.1, ECO:0000313|Proteomes:UP000190539}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F601 {ECO:0000313|EMBL:OON82179.1,
RC   ECO:0000313|Proteomes:UP000190539};
RA   Zong G., Zhong C., Fu J., Qin R., Cao G.;
RT   "Draft Genome Sequence of Streptomyces tsukubaensis F601, a Producer of the
RT   immunosuppressant tacrolimus FK506.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OON82179.1}.
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DR   EMBL; MVFC01000002; OON82179.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V4AFP0; -.
DR   STRING; 83656.B1H18_03820; -.
DR   OrthoDB; 9806785at2; -.
DR   Proteomes; UP000190539; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR   InterPro; IPR004710; Bilac:Na_transpt.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   PANTHER; PTHR10361:SF28; RH04535P; 1.
DR   PANTHER; PTHR10361; SODIUM-BILE ACID COTRANSPORTER; 1.
DR   Pfam; PF01758; SBF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190539};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        24..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        81..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        138..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        204..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        234..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          323..343
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   343 AA;  34627 MW;  938B60BB15548811 CRC64;
     MRTEQTTPSD SGAPDNGDKA AKRAVTVFPV LVLVAGVAGL VTPGTFAGWG DSVPYLLGIV
     MFCMGLTMTP LDFKGVAKRP WAVAIGLVAH YVIMPGLGWL IAHLLGLPPQ LAAGVILVGC
     APSGTASNVV TFLARGDVAL SVSVATVSTV LAPLITPPLT LLLAGEYLPV DAGSMMSDIL
     KTVLLPVLGG LVVRLVAGKV IDRVLGVMPW LSSVAIAAIV AAVVAGSADT IKGAAVSVLI
     AVVLHNGLGL ALGYGAGKVA KLGPPASRAM AFEVGMQNSG LAASLASAHF SPLAALPAAV
     FSVWHNVSGA LVAAWMSHRS RGEEPVAVET TGGATTPSWA RQD
//