ID   A0A1V4AG15_9ACTN        Unreviewed;       709 AA.
AC   A0A1V4AG15;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=Hydantoinase {ECO:0000313|EMBL:OON82309.1};
GN   ORFNames=B1H18_04565 {ECO:0000313|EMBL:OON82309.1};
OS   Streptomyces tsukubensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=83656 {ECO:0000313|EMBL:OON82309.1, ECO:0000313|Proteomes:UP000190539};
RN   [1] {ECO:0000313|EMBL:OON82309.1, ECO:0000313|Proteomes:UP000190539}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F601 {ECO:0000313|EMBL:OON82309.1,
RC   ECO:0000313|Proteomes:UP000190539};
RA   Zong G., Zhong C., Fu J., Qin R., Cao G.;
RT   "Draft Genome Sequence of Streptomyces tsukubaensis F601, a Producer of the
RT   immunosuppressant tacrolimus FK506.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OON82309.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MVFC01000002; OON82309.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V4AG15; -.
DR   STRING; 83656.B1H18_04565; -.
DR   OrthoDB; 9768323at2; -.
DR   Proteomes; UP000190539; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.30.420.40; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000190539}.
FT   DOMAIN          7..175
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          194..501
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
SQ   SEQUENCE   709 AA;  73110 MW;  39622BF371B7EF4E CRC64;
     MTTHRVRVGI DVGGTFTDAV AVDATTLELL GQVKVPTSHH HEDGVAHGIV EALDRLLEQT
     GRAPEDVTFL AHGTTQATNA LLEGDVAPVG LIGIGAGPGG VLTRRLASLG KLELTPGKRL
     PLSYAHVADP RDTAEAGRAV ARVREAGAEV LVASQPFSVD VPDGEDAVLA TARHEGLPMT
     AAHEITSLYG LSKRTRTAVV NAAIMPKMLA TADLVDASIT KAGVSAPLMV MRCDGGVMSL
     DEMRRRPLLT ILSGPAAGVA GALMRERISE GVFLETGGTS TDISVVRRGK VAVRHATVLG
     KTSYLNALDV RTVGVGGGSM VRIGGGRVTG VGPRSAHIAG LPYACFADLE ELRDAKLTTV
     RPMEDDPADY AVLDAAGGRY AITMTCAANA LGRVPDGDFA RSDPETARAA LAPLAEALST
     DVAGAAAQLL DAGTAQVRSV VDAMSADYRL DKDAVVLVGG GGGAASVTPH LAATVGLEGR
     IAAHSEVISP IGVALALVRE QIERQVPGAT QEQILAVRAE AERAVVAQGA SPEGVEVEVT
     VDPQTSTVRA VATGATELRT QDRAHRADDA ERLRAAAGSL KADPSSVRVL AGTAAHTVYG
     TEVRRRFRAT RHPVRVVDSD GVVRLHAPDA RVETTTVAAA PTVLGELVRE TTSYGDGGVR
     APALRLLIGS RIADLSGVLD AGALLALADS ELRGREAGEA VVAVVEVRS
//