ID   A0A1V4CLI5_9BURK        Unreviewed;       338 AA.
AC   A0A1V4CLI5;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=NADP-dependent oxidoreductase {ECO:0000313|EMBL:OPF65664.1};
GN   ORFNames=BC358_03765 {ECO:0000313|EMBL:OPF65664.1};
OS   Hydrogenophaga sp. H7.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Hydrogenophaga.
OX   NCBI_TaxID=1882399 {ECO:0000313|EMBL:OPF65664.1, ECO:0000313|Proteomes:UP000189907};
RN   [1] {ECO:0000313|Proteomes:UP000189907}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H7 {ECO:0000313|Proteomes:UP000189907};
RA   Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OPF65664.1}.
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DR   EMBL; MCIC01000001; OPF65664.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V4CLI5; -.
DR   STRING; 1882399.BC358_03765; -.
DR   OrthoDB; 9805663at2; -.
DR   Proteomes; UP000189907; Unassembled WGS sequence.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd05288; PGDH; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR041694; ADH_N_2.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR045010; MDR_fam.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR   PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR   Pfam; PF16884; ADH_N_2; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189907}.
FT   DOMAIN          17..335
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   338 AA;  36289 MW;  F7AA779A4C9749A0 CRC64;
     MATNRQILLD NRPEGEATVN NFKLVTTETP PLKDGQVLVR HHFLSLDPYM RGRMNDSKSY
     AASQPLGEVM IGGTVGEVVE SRHPKFLTGD RVVGMGGWQE YSVVDALQPG ALRKVDTTHV
     PLSYYLGAVG MPGVTAWYGL VKIINPKAGE TMVISAATGA VGSAFGALAK ARGCRVVGIA
     GGPEKCAYAV NELGFDACID YRAHKDMYSL AKALKQECPN GIDGYFENVG GMVLDAVLLR
     MNAFGRIAVC GMIAGYDGQP LPLANPALIL INRLKVEGFI VSEHMEVWPE ALTELGTLVA
     QGKLRPRETI AQGLENAPEA FMGLLKGKNF GKQLVKLV
//