ID A0A1V4D2Y9_9ACTN Unreviewed; 403 AA.
AC A0A1V4D2Y9;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=tRNA dihydrouridine synthase DusB {ECO:0000313|EMBL:OPF78142.1};
GN ORFNames=VT50_0220125 {ECO:0000313|EMBL:OPF78142.1};
OS Streptomyces antioxidans.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1507734 {ECO:0000313|EMBL:OPF78142.1, ECO:0000313|Proteomes:UP000033615};
RN [1] {ECO:0000313|EMBL:OPF78142.1, ECO:0000313|Proteomes:UP000033615}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUSC164 {ECO:0000313|Proteomes:UP000033615};
RA Lee L.-H., Ser H.-L.;
RT "Genome sequence of Streptomyces antioxidans MUSC 164.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPF78142.1}.
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DR EMBL; LAKD02000049; OPF78142.1; -; Genomic_DNA.
DR RefSeq; WP_046086796.1; NZ_LAKD02000049.1.
DR AlphaFoldDB; A0A1V4D2Y9; -.
DR OrthoDB; 9764501at2; -.
DR Proteomes; UP000033615; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0017150; F:tRNA dihydrouridine synthase activity; IEA:InterPro.
DR CDD; cd02801; DUS_like_FMN; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR035587; DUS-like_FMN-bd.
DR InterPro; IPR004652; DusB-like.
DR InterPro; IPR024036; tRNA-dHydroUridine_Synthase_C.
DR InterPro; IPR018517; tRNA_hU_synthase_CS.
DR NCBIfam; TIGR00737; nifR3_yhdG; 1.
DR PANTHER; PTHR45846; TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE; 1.
DR PANTHER; PTHR45846:SF1; TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE; 1.
DR Pfam; PF01207; Dus; 1.
DR SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
DR PROSITE; PS01136; UPF0034; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 28..348
FT /note="DUS-like FMN-binding"
FT /evidence="ECO:0000259|Pfam:PF01207"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 403 AA; 43396 MW; 897EA34129B58783 CRC64;
MTQSPQTPPT ERTPLRIGPH TVQPPVVLAP MAGITNAPFR TLCREFSGGR GLFVSEMITT
RALVERDAKT MRLIHFDGTE KPRSIQLYGV DPVTVGKAVQ MIVDEDLADH IDLNFGCPVP
KVTRKGGGSA LPYKRRLLRS ILREAVTAAG PLPVTMKMRK GIDDDHITYL DAGRIAVEEG
VTAIALHGRT AAQHYGGTAD WEAIARLKEA VPEIPVLGNG DIWSADDAVR MMRETGCDGV
VVGRGCLGRP WLFGDLVAAF EPGAAASRPG PGAPVSGPVA SGYARPTLKE VAAVMRRHAE
LLAEWLEDEE RGVIDFRKHV AWYTKGFSVG SEMRKRLAIT SSLAELDALL AELDLDQEWP
PGADGPRGRT SGRNRVVLPD GWLDDPYDCA GVAAEAELDT SGG
//
