ID A0A1V4DTH2_9ACTN Unreviewed; 629 AA.
AC A0A1V4DTH2;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Glucosylceramidase {ECO:0000313|EMBL:OPG04033.1};
GN ORFNames=B1R27_26560 {ECO:0000313|EMBL:OPG04033.1};
OS Streptomyces sp. GKU 895.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1662404 {ECO:0000313|EMBL:OPG04033.1, ECO:0000313|Proteomes:UP000190311};
RN [1] {ECO:0000313|EMBL:OPG04033.1, ECO:0000313|Proteomes:UP000190311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GKU 895 {ECO:0000313|EMBL:OPG04033.1,
RC ECO:0000313|Proteomes:UP000190311};
RA Kruasuwan W.;
RT "Draft genome sequence of plant growth promoting endophytic Streptomyces
RT sp. GKU 895 isolated from root of sugarcane plants.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC {ECO:0000256|ARBA:ARBA00005382, ECO:0000256|RuleBase:RU361188}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPG04033.1}.
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DR EMBL; MWJO01000070; OPG04033.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4DTH2; -.
DR Proteomes; UP000190311; Unassembled WGS sequence.
DR GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR033452; GH30_C.
DR InterPro; IPR001139; Glyco_hydro_30.
DR InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR Pfam; PF02055; Glyco_hydro_30; 1.
DR Pfam; PF17189; Glyco_hydro_30C; 1.
DR Pfam; PF00652; Ricin_B_lectin; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361188};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361188};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..629
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013116019"
FT DOMAIN 501..629
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
SQ SEQUENCE 629 AA; 66375 MW; C4225C0F282B09BA CRC64;
MRRTPHARRA PQALRLLLAG VLSAAGVTAA TAPAHAAGEQ VTAWLTTTDD SAGRHVTRGL
QAQTPFAFQS GAGGGGENIT VDENTRYQTF TGGGASFTDT AAWLMNSSGA LSQTTRDATM
RKLFSPTDGI GLSFLRNPMG ASDLARYGYT YDDVPAGQTD PNLNSFSIAH DLADVVPLTK
QALQLNPSLT VMASPWTAPA WMKDSGSLNG GWLKAEDYGA YANYFVKYLQ AYKDQGVPVS
YVTVQNEPTC CSGYPSMSWN ASGLAYFTKS ELLPKLNASG LSTKVLAHDW NWDVYDSYAA
ATVDDAAVRS NPNFGGIAWH GYSDISGVSK QTTVHNQYPT LDAFGTEHSG GTWIANQQRE
DMNNIIDYTR NWAKSVTKWS LAVDQNMGPH NGGCGTCTGL ITVHNGDGAS GTVDYTVEYY
TMGHLTKFVR PGAQRIASTA SSAVPNVAWR NPDGSKALIA YNDASSARTV TINWGSQHAT
YSLPGKTSAT FTWTGTQSGS GSSSGSFVGL AGKCLDVAGG SATNGTAVQL YDCNGSTAQQ
WTVQSDGSVR ALGKCLDVTS ASVADGAKVQ LYDCNGTGAQ QWSYNASTGD VVNTAANKCL
DVTGNSSANG ARAQIWSCTG AANQKWHLQ
//
