ID   A0A1V4I7Q5_9FIRM        Unreviewed;       414 AA.
AC   A0A1V4I7Q5;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Thioredoxin reductase {ECO:0000313|EMBL:OPJ56018.1};
DE            EC=1.8.1.9 {ECO:0000313|EMBL:OPJ56018.1};
GN   Name=trxB_3 {ECO:0000313|EMBL:OPJ56018.1};
GN   ORFNames=CLOTH_11960 {ECO:0000313|EMBL:OPJ56018.1};
OS   [Clostridium] thermoalcaliphilum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae.
OX   NCBI_TaxID=29349 {ECO:0000313|EMBL:OPJ56018.1, ECO:0000313|Proteomes:UP000190140};
RN   [1] {ECO:0000313|EMBL:OPJ56018.1, ECO:0000313|Proteomes:UP000190140}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7309 {ECO:0000313|EMBL:OPJ56018.1,
RC   ECO:0000313|Proteomes:UP000190140};
RA   Poehlein A., Daniel R.;
RT   "Genome sequence of Clostridium thermoalcaliphilum DSM 7309.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OPJ56018.1}.
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DR   EMBL; MZGW01000003; OPJ56018.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V4I7Q5; -.
DR   STRING; 29349.CLOTH_11960; -.
DR   OrthoDB; 9776839at2; -.
DR   Proteomes; UP000190140; Unassembled WGS sequence.
DR   GO; GO:0004791; F:thioredoxin-disulfide reductase (NADP) activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   PANTHER; PTHR42949; ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT B; 1.
DR   PANTHER; PTHR42949:SF3; OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:OPJ56018.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190140}.
FT   DOMAIN          3..296
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   414 AA;  45806 MW;  EAB2E88C433215F3 CRC64;
     MKYDVVIIGG GPAGLGAAIE AKRTGAKKVI ILERDRELGG ILNQCIHNGF GLHEFKEELT
     GPEYASRFID MVKEFNIEYM LNTMVLSIDE NRNIVALGER GLIDISARAI VLAMGCIERS
     RGAIDVPGYR GAGIYTAGAA QRFMNMEGYM VGKRVVIYGS GDIGLIMARR LTLEGAKVEA
     VVERNPFSSG LNRNIVQCLN DYNIPLLLSH CISYVHGRDR VNGVTISKLD ENMDIIHESS
     KFIECDTLLL SVGLIPENEL SREVNINLDN TTRGPVVNSS METNIEGIFA CGNVVHVHDL
     VDFVTKESRI AGRNAAIYAL GENKDKSYVK TKGGNGISYI VPQYIDTNSN ENIDLFMRVR
     NIYENKKLII RCGEKIILEK SRLHMIPSEM ENIKLSPHIL KKINGDIEIC VEGA
//