ID   A0A1V4IBE6_9FIRM        Unreviewed;       294 AA.
AC   A0A1V4IBE6;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Tyrosine recombinase XerD {ECO:0000313|EMBL:OPJ56965.1};
GN   Name=xerD_1 {ECO:0000313|EMBL:OPJ56965.1};
GN   ORFNames=CLOTH_02470 {ECO:0000313|EMBL:OPJ56965.1};
OS   [Clostridium] thermoalcaliphilum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae.
OX   NCBI_TaxID=29349 {ECO:0000313|EMBL:OPJ56965.1, ECO:0000313|Proteomes:UP000190140};
RN   [1] {ECO:0000313|EMBL:OPJ56965.1, ECO:0000313|Proteomes:UP000190140}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7309 {ECO:0000313|EMBL:OPJ56965.1,
RC   ECO:0000313|Proteomes:UP000190140};
RA   Poehlein A., Daniel R.;
RT   "Genome sequence of Clostridium thermoalcaliphilum DSM 7309.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC       the cutting and rejoining of the recombining DNA molecules.
CC       {ECO:0000256|ARBA:ARBA00003283}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC       {ECO:0000256|ARBA:ARBA00008857}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OPJ56965.1}.
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DR   EMBL; MZGW01000001; OPJ56965.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V4IBE6; -.
DR   STRING; 29349.CLOTH_02470; -.
DR   OrthoDB; 9801717at2; -.
DR   Proteomes; UP000190140; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   PANTHER; PTHR30349; PHAGE INTEGRASE-RELATED; 1.
DR   PANTHER; PTHR30349:SF87; PROPHAGE INTEGRASE INTD-RELATED; 1.
DR   Pfam; PF02899; Phage_int_SAM_1; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000190140}.
FT   DOMAIN          1..85
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000259|PROSITE:PS51900"
FT   DOMAIN          106..292
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000259|PROSITE:PS51898"
SQ   SEQUENCE   294 AA;  34303 MW;  1A1E956CAA0347C1 CRC64;
     MEDNIIHKYT DYIQKERNLS DNTINSYSVD LKKYLEYLRK ENINIYDVTE NDIFSFLIYL
     EKSNISTSTI SRMISSIKSF YDFLFLSKLI DANPTAKLKK PKVTRDKIEI LTEEEIEKML
     NSPNLSTAKG MRDKAILETL YGTGMKVSEL IKLDIDDLNL NMEYLICTSS KTSRTIPLSN
     ITQKYIIKYL EDAREKIVKN SDQRALFVNS KGERFTRQGL WKLIKSYTND NEINKNVTPT
     MLRHSFAIHL LKNGADMSIV NRLLGNTNLS SLQAYLIHMD KNIREEFRQK HPRI
//