ID A0A1V4INR7_9CLOT Unreviewed; 575 AA.
AC A0A1V4INR7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Iron hydrogenase 1 {ECO:0000313|EMBL:OPJ61688.1};
DE EC=1.12.7.2 {ECO:0000313|EMBL:OPJ61688.1};
GN ORFNames=CLORY_21880 {ECO:0000313|EMBL:OPJ61688.1};
OS Clostridium oryzae.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1450648 {ECO:0000313|EMBL:OPJ61688.1, ECO:0000313|Proteomes:UP000190080};
RN [1] {ECO:0000313|EMBL:OPJ61688.1, ECO:0000313|Proteomes:UP000190080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 28571 {ECO:0000313|EMBL:OPJ61688.1,
RC ECO:0000313|Proteomes:UP000190080};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Clostridium oryzae DSM 28571.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ61688.1}.
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DR EMBL; MZGV01000020; OPJ61688.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4INR7; -.
DR STRING; 1450648.CLORY_21880; -.
DR OrthoDB; 9805142at2; -.
DR Proteomes; UP000190080; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.740; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.1780; -; 1.
DR Gene3D; 4.10.260.20; Iron hydrogenase, small subunit; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR InterPro; IPR036991; Fe_hydrogenase_ssu_sf.
DR InterPro; IPR013352; Fe_hydrogenase_subset.
DR InterPro; IPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd.
DR NCBIfam; TIGR02512; FeFe_hydrog_A; 1.
DR NCBIfam; NF040762; Hydr_FeFe_Clost; 1.
DR PANTHER; PTHR11615:SF6; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS51839; 4FE4S_HC3; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:OPJ61688.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000190080}.
FT DOMAIN 2..76
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 76..115
FT /note="4Fe-4S His(Cys)3-ligated-type"
FT /evidence="ECO:0000259|PROSITE:PS51839"
FT DOMAIN 136..163
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 179..208
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 575 AA; 63341 MW; CCE9529B54777FA4 CRC64;
MKKVIINGKE VTTDEELSIL ELARQNGIDI PSLCFLKDCG NFGKCGVCLV EADGKVIASC
VAKVKDGMVI NTETEEVKER IKKRVSMLLD KHEFKCGPCP RRENCEFLKL VIKTKAKANT
PFLPTDKSQY IDNRSNAIEI DRSKCVLCGR CVAACKAFTK TESIQFIKKD GQRAVGTVDD
RCFDDTNCLL CGQCVIACPV AALHEKSHIE RVKAALADPE KHVVVAIAPA VRTALGELFN
MGFGKDVTGK IYAALRALGF SKVFDINFGA DMTIMEEATE LIQRIKAGGP FPMFTSCCPA
WVRQAQNYFP QFLENLSSAK SPQQIFGTAS KTYYPSIEGI DPKSVYTVTI MPCNDKKYEA
DLPDMEVDGL RHIDAVLTTR ELAKMIKEAK IKFAELEDET ADPAMGEYSG AGVIFGATGG
VMEAALRTAK DFAENTELEN IDYKEVRGLK GIKEATIEIA GEKYNVAVIN GAANMFDFVN
SGKINEKQYH FIEVMACPGG CINGGGQPHI NAAARDSVDY KTMRASVLYN QDLNLPKRKS
HKNTAIIKMY DSYFGKPGEG LAHKLLHYKA KERNK
//
