ID A0A1V4IQR2_9CLOT Unreviewed; 597 AA.
AC A0A1V4IQR2;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CLCHR_21620 {ECO:0000313|EMBL:OPJ62219.1};
OS Clostridium chromiireducens.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=225345 {ECO:0000313|EMBL:OPJ62219.1, ECO:0000313|Proteomes:UP000191056};
RN [1] {ECO:0000313|EMBL:OPJ62219.1, ECO:0000313|Proteomes:UP000191056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23318 {ECO:0000313|EMBL:OPJ62219.1,
RC ECO:0000313|Proteomes:UP000191056};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Clostridium chromiireducens DSM 23318.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ62219.1}.
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DR EMBL; MZGT01000025; OPJ62219.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4IQR2; -.
DR STRING; 225345.CLCHR_21620; -.
DR OrthoDB; 9809348at2; -.
DR Proteomes; UP000191056; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OPJ62219.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000191056};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OPJ62219.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 319..372
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 483..587
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 367..394
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 597 AA; 68597 MW; 7D992286EF6EE1F0 CRC64;
MYKGLRKIIS KLSKMKFNQK ITIFFILAVL ITNSFVIFAV YQLAGKQITE KSSGLVQGQF
ETTTDILNIT LKNIIETSNI ITGDSRVKEF LMNNKFTSKN YNKDTSDAYS SVRYFLDSNS
YIDYISLVKF DGPELIYVGE TWTSGDFRTE TLKDYQQAVG TKFGNCKISM KRKVFYPYQY
VLNIYQPIYD KYNYNKYTGF LVIGIGEKSI KEFYSNLDKG LRVQTYLTDK DGVIISNEDK
SLIGTDSFYK DVLQGKSGQQ KVGNKMVIYE KLDNWDWYMV GEIPTESMLK DTNTMIFLII
TLVLGAGGLI SLAFYKLSNN LYKPVDALVS TMREVSMGNL EVRMKRDYKG KDFRQLASGF
NIMIEEINIL MYRIKREQNE IKQIELNRLQ SQIKPHFLYN TLECIHWQAL SDGNKDVSRM
VKALANYYRL CLSKGKDIIQ LSQELANIEN YLIIQNMRYS GIAQCDINVD DKFKNVLIPK
LTLQPLIENS IYHGIRVKDG FKGEIFVTAE EKENKIVISV SDNGVGMTQE QIDEINNSIS
VFDEKTGYGL RNVHKRIEIL FGSGYGLYYR KSKYGGTTVD ILLPKGENGE NNKCIRL
//
