ID A0A1V4J1C6_9CLOT Unreviewed; 450 AA.
AC A0A1V4J1C6;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Putative gluconeogenesis factor {ECO:0000256|HAMAP-Rule:MF_00973};
GN Name=yvcK {ECO:0000313|EMBL:MVX62957.1};
GN ORFNames=CLCHR_03870 {ECO:0000313|EMBL:OPJ65814.1}, D2A34_04940
GN {ECO:0000313|EMBL:RII36732.1}, GKZ28_04470
GN {ECO:0000313|EMBL:MVX62957.1};
OS Clostridium chromiireducens.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=225345 {ECO:0000313|EMBL:OPJ65814.1, ECO:0000313|Proteomes:UP000191056};
RN [1] {ECO:0000313|EMBL:OPJ65814.1, ECO:0000313|Proteomes:UP000191056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23318 {ECO:0000313|EMBL:OPJ65814.1,
RC ECO:0000313|Proteomes:UP000191056};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Clostridium chromiireducens DSM 23318.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:RII36732.1, ECO:0000313|Proteomes:UP000265930}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C1 {ECO:0000313|EMBL:RII36732.1,
RC ECO:0000313|Proteomes:UP000265930};
RA Xing M., Wei Y., Ang E.L., Zhao H., Zhang Y.;
RT "Genome of Clostridium chromiireducens C1, DSM12136.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:MVX62957.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NM79_F5 {ECO:0000313|EMBL:MVX62957.1};
RA Navarre W., Wong E.;
RT "Microbes associate with the intestines of laboratory mice.";
RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis under gluconeogenic growth
CC conditions. {ECO:0000256|HAMAP-Rule:MF_00973}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00973}.
CC -!- SIMILARITY: Belongs to the gluconeogenesis factor family.
CC {ECO:0000256|HAMAP-Rule:MF_00973}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ65814.1}.
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DR EMBL; WSRQ01000005; MVX62957.1; -; Genomic_DNA.
DR EMBL; MZGT01000004; OPJ65814.1; -; Genomic_DNA.
DR EMBL; QXDJ01000001; RII36732.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4J1C6; -.
DR STRING; 225345.CLCHR_03870; -.
DR OrthoDB; 9783842at2; -.
DR Proteomes; UP000191056; Unassembled WGS sequence.
DR Proteomes; UP000265930; Unassembled WGS sequence.
DR Proteomes; UP000656077; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043743; F:LPPG:FO 2-phospho-L-lactate transferase activity; IEA:InterPro.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR CDD; cd07187; YvcK_like; 1.
DR Gene3D; 3.40.50.10680; CofD-like domains; 1.
DR HAMAP; MF_00973; Gluconeogen_factor; 1.
DR InterPro; IPR002882; CofD.
DR InterPro; IPR038136; CofD-like_dom_sf.
DR InterPro; IPR010119; Gluconeogen_factor.
DR NCBIfam; TIGR01826; CofD_related; 1.
DR PANTHER; PTHR30135:SF3; GLUCONEOGENESIS FACTOR-RELATED; 1.
DR PANTHER; PTHR30135; UNCHARACTERIZED PROTEIN YVCK-RELATED; 1.
DR Pfam; PF01933; CofD; 1.
DR SUPFAM; SSF142338; CofD-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00973};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000191056};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 450 AA; 50201 MW; 68BC5199D3C62C73 CRC64;
MRIRDWLKAG IKVKRWLAFG VFGILLIAFG FTELVTHRVY DLYYRVFYVC LNITGIFVLY
ISVTETMKSM IALVNRGYIK VSLDSRKIES LIYEKRLLVK GPKIVVIGGG TGLSTMLRGL
KYYTSNITAI VTVGDDGGGS GDLREDLGML PPGDIRNCIL ALADTEPIME DLLQYRFPDG
RLKNQSFGNL FLAAMAGISD NFEEAVQKMS SVLAVTGKVI PVTLDNMQLV AKLQNGNIVK
GESQIPEEAI EQKSRIEELK IVPENAKALP ESLQAIREAD AIVMGPGSLY TSITSNLLVK
EIAKEVRKSD AIKIYISNIM TQPGETTGFK VSDHLKVLFK YGGKDIVDYV IANTGEITDE
LKEKYQKDGA ELVKLDREDI NSLGVKIVGE DLVKIKNGLV KHDSGKLAEI LADTIMEKKL
LYDKKKIIEY MYLSQRIKER VREEKGQIID
//
