ID A0A1V4J5A1_PATFA Unreviewed; 2169 AA.
AC A0A1V4J5A1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 22-FEB-2023, entry version 20.
DE SubName: Full=FRAS1-related extracellular matrix protein 1 isoform B {ECO:0000313|EMBL:OPJ67224.1};
GN Name=FREM1 {ECO:0000313|EMBL:OPJ67224.1};
GN ORFNames=AV530_001463 {ECO:0000313|EMBL:OPJ67224.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ67224.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ67224.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ67224.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ67224.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FRAS1 family.
CC {ECO:0000256|ARBA:ARBA00005529}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ67224.1}.
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DR EMBL; LSYS01009308; OPJ67224.1; -; Genomic_DNA.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR CDD; cd00037; CLECT; 1.
DR Gene3D; 2.60.40.2030; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR003644; Calx_beta.
DR InterPro; IPR039005; CSPG_rpt.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR045658; FRAS1-rel_N.
DR PANTHER; PTHR45739:SF7; FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1; 1.
DR PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF16184; Cadherin_3; 12.
DR Pfam; PF03160; Calx-beta; 1.
DR Pfam; PF19309; Frem_N; 1.
DR Pfam; PF00059; Lectin_C; 1.
DR SMART; SM00237; Calx_beta; 1.
DR SMART; SM00034; CLECT; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF141072; CalX-like; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
DR PROSITE; PS51854; CSPG; 11.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..2169
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012663401"
FT REPEAT 293..387
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 412..499
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 520..614
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 641..753
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 775..866
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 886..981
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1024..1126
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1147..1256
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1277..1374
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1491..1581
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1615..1709
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT DOMAIN 2050..2157
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT REGION 1839..1908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2169 AA; 244098 MW; CC3BACCC2B3B4821 CRC64;
MKPFEKSWLF LVLLVVLRVV CSSFISVNIG VKVMKGQSVF LSEDDLKFSI PREKDVCKVE
VVINEPITQR VGKLTPQVFD CHFLPNEVKY THNGCPILDE DVVMLRLYRF TETETFVETF
TLHVQLLEPD CNIIKMRSHA LEVPEYYGLS RVIDKNILTF DYDRKINLDC TISIVSLETH
LPAHGQLITG EVQQEHLHGD QPQRFLPGPK HSLDQQCRNG SCMLGLGGVH DTKMSCEEFL
RMGIRYRHLD PPSPDTDYIP VRLDLTDSRS KTLHKTEYAW LPVQIKGAIP NQIPKAATMA
KFILEVNQFI LTPITTTTID AEDNETPKSL LVFNITKPPP QGFITHLSDH TKPIGSFTWK
DLSDMLIAYQ PPNNSHTERR NYEVEFEVHD FYFERSLPIT VHLSIRTTET NAPRVSWNTG
LNLLEGQSRP ITWQHFQIVD NDNIQNVRLV TVDGLHHGQL TVRGGKGFIF TVSDIQAGVV
HYHHDDSDST KDVVVFRIFD GLHSIRHKFP INILPKDDSP PFLISNVVIE VREGQMILIQ
GSMLHASDMD SSDDYILFNI TKPPQAGEIM KKPGPNLIGY SVSSFLQRDL FNGIIYYRHL
GGEVFEDSLE FVLCDSHDPP NLSEPQVMMV HITSVDDQLP REAPGVTRHL VVKETEIAHL
TKKHLHFIDV EEQDRELTYT ITTSPFFSCT HSHSDAGKLF MVDTIPKLVK DPAALALQSF
TQHAVNYMKI AYMPPLQDIG PEPQQVQFIF SISNQHGGTL YGICFNITIL PVDNQAPEVF
TSHLRVEEGG LSPVTEGHIL ISDVDTKQEH LFLLLQKQPQ HGVVELDGFP MKEGDRLSCG
DLRTLAVRYR HDGSETLTDI VLFAATDGIH FVEFILQVKV LPVNDEPPVM RTGLVPVLHC
LEGEEVVLST DHIYATDADS DDMKLTFILS RQPYHGVVRK AGIAVDRFSQ ADVVSGLVTY
KHIGGEIGLT PSIEILTFVV SDGEAGLDVK GCCHDGPLPS PVLIHDPFAV YDLNITVLPV
DNQPPSIATG ARFVVEEGSS AALTTNHLFA TDPDTPAEDL EFVLVSPPQF GYLENILPSP
GFEKSNIGIS IASFQLKHLK ALNINYVQAR HMRMEPTADH FVLYVTDGLH HSAETPFFVL
INPTNDEVPE FTARNITVQE GEMRELDLSV INAVDLDVPQ DHLVFGVVRG PWHGFIIKGV
DGNDILHYKQ LINHNQHSHG LLVHEFSMEL LKNGMKLMYI HDNSENLTDS FEIQLSDGKH
KVLRTISVKV IPVNDEKPVL SKKVDIEVNM GETRIISSAV LSAEDKDTPR EKIYYLFERL
PENGQLQLKV GQGWMTLQTG MKCTQEELDM NLVRYAHTGA IGSKNQDRFT FHLWDGYNRS
PAVDFYINIK DMEKGDIAVF IKPLRVSKGD RSYITTDVLL VLDGTDKPEE LLYVITSPPQ
YGQIEFLQYM VNQEHMLKTT LPLFARFIIS NGLRTKHGSF MISLEAVDQD LPTLSRNTGL
RLVEGTTAFL SPDVLQLSDP DTAKENLTFL LAQLPQYGHL YYRGAMLLQY NFTQQDVDNR
DVAYKHGGGD SQTDRFTFVA TDRTNQGFIM NGRVQSEPVA FTIQVDRLDK IAPKIIHLRC
FSDVEVLKSG NYGIYITARS LKASDPNTED DKIMFRILRG PQYGYLENIT TGGFIQEWFS
QKDLNSKIIL YVINPSQEVN SDNIEFQVTD ARGNSAVPQR LELQWSRIEM QQTEYEVCES
AGVVSLKIAR AGHSAQSAFI AVKVNEISAT LGKDFTVTSS KLVQFDPGMS TKTWNIAITY
DELEEDDEVF EVVLNSPVNA VLGTQTKAVV RILDSKGGQC SYSHPSGQRK HDFSVRGTLL
PVSSGSSSPP RPGTAPLEGI PRPPSKGMRE HGGDPRQEHS LTNQSRTSLR VIGNGRIVHP
SSIFRNGTDV VFKYHGMVSL KIEDDSSSTK ANKKAQVSVI NQAQPQINVV SSRKTEIPQA
DKAEVASEPS SRHQDFNSFP KACTPDLKGL LHYEESTQKL FQCDGIIWQL WNLQSKEEST
KKCPSGWSHH EGSCYFLVVN HKVTWNTAAR ACREQYLGSL ASVANEQHMQ WLWDFSGRKP
FWIGLNAQVN PGHWEWNGGE PVTYINWRKG SYHFPKRGRN CVLVQKQGKW QATHCRKVKR
NSYICSRKL
//
