ID A0A1V4J606_PATFA Unreviewed; 1519 AA.
AC A0A1V4J606;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};
GN Name=SEC16A {ECO:0000313|EMBL:OPJ67672.1};
GN ORFNames=AV530_001926 {ECO:0000313|EMBL:OPJ67672.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ67672.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ67672.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ67672.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ67672.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in the organization of the endoplasmic reticulum
CC exit sites (ERES), also known as transitional endoplasmic reticulum
CC (tER). Required for secretory cargo traffic from the endoplasmic
CC reticulum to the Golgi apparatus. {ECO:0000256|RuleBase:RU364101}.
CC -!- SUBUNIT: SEC16A and SEC16B are each present in multiple copies in a
CC heteromeric complex. {ECO:0000256|RuleBase:RU364101}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004406}. Golgi apparatus membrane
CC {ECO:0000256|RuleBase:RU364101}.
CC -!- SIMILARITY: Belongs to the SEC16 family.
CC {ECO:0000256|ARBA:ARBA00005927, ECO:0000256|RuleBase:RU364101}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ67672.1}.
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DR EMBL; LSYS01008925; OPJ67672.1; -; Genomic_DNA.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IEA:UniProt.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006914; P:autophagy; IEA:InterPro.
DR GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd09233; ACE1-Sec16-like; 1.
DR Gene3D; 1.25.40.1030; -; 1.
DR InterPro; IPR024298; ACE1_Sec16_Sec31.
DR InterPro; IPR024880; Sec16.
DR InterPro; IPR024340; Sec16_CCD.
DR PANTHER; PTHR13402:SF13; PROTEIN TRANSPORT PROTEIN SEC16A; 1.
DR PANTHER; PTHR13402; RGPR-RELATED; 1.
DR Pfam; PF12932; Sec16; 1.
DR Pfam; PF12931; Sec16_C; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|RuleBase:RU364101};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|RuleBase:RU364101};
KW Golgi apparatus {ECO:0000256|RuleBase:RU364101};
KW Membrane {ECO:0000256|RuleBase:RU364101};
KW Protein transport {ECO:0000256|RuleBase:RU364101};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Transport {ECO:0000256|RuleBase:RU364101}.
FT DOMAIN 603..700
FT /note="Sec16 central conserved"
FT /evidence="ECO:0000259|Pfam:PF12932"
FT DOMAIN 772..1006
FT /note="Ancestral coatomer element 1 Sec16/Sec31"
FT /evidence="ECO:0000259|Pfam:PF12931"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1048..1069
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1159..1361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1411..1519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..549
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..570
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1050..1065
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1181..1204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1220..1260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1271..1285
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1299..1332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1333..1349
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1486..1505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1519 AA; 166524 MW; 00B9B71A9BCD218D CRC64;
MQAPLSEQFY PQPPLQDSNR DSGTLSMFFK GDEAENEEIL SSEKNYIAQT GTGSANEMVQ
RGMDAQYFPK IIDSSPLGGD SSELNLSKNY HSNLSQPPTP SPPKPTGVFH TSANSSFEPV
RSHGVGIKPA EIDQAKMVVE LRENHSNQKN IKKNTAVPVA SPGNLEQPPD NLETIFMPQL
SQDGNISSEN LENPPKMGEE EALQSQVTKD VQAVSDRAVQ GVLPSPPQMQ AAQMQQPPSS
GPSSVPLNYQ GATGTKVTQA SQQHENQVLS NHPQPAGSQE ASSAQPTRYN QTSPDKQPAS
GQPSGAPPST TPSTTSQSVT SSAQQDLQRP SLPQTPQEAF GPPQNPYYYY RHPYDAYQPP
YPPPYAPADP RTAAHLYYMD DSYGQYDPRY RHYESGTAYV EPGSYRYAEP ERPSSRASHC
SDRPSSRQGY TEDYYPKTGW SDYYPGYYPN SYDYGDPSRW DHYASAYDPR YRDPRGYDQR
YWYDAEHNPY QKRDGYPYSS RYDRYEDNWR YDPRFAGSFD DESEPHRDPY GDDFDRRSVH
SEHSGHSLRS SRSVHSHQSS FSSRSQQPFT DYGYAAEPGW PAVEQAPLRP STPEKFSVPH
ICARFGPGGF LIKVLPNLPS EGQPALVEIH SMETMLQHSP EQEEMRAFPG PLAKDDTHKV
DVINFAQNKA TQCFKNENLI DKESASLLWD FIVLLCRQNG TVVGTDLAEL LLRDHKTVWL
PGKSPNEANL IDFTNEALEQ VEEESGEAQL SFLTDSLITT IDSLEKETER FRELLLYGRK
KDALESAMKH GLWGHALLLA SKMDSRTHAR VMTRFANSLP INDPLQTVYQ LMSGRMPAAS
TCCGDEKWGD WRPHLAMVLS NLTNNVDLES RTIATMGDTL ASKGLLDAAH FCYLMAQVGF
GVYTRKTTKL VLIGSNHSLP FFKFATNEAI QRTEAYEYAQ SLGTQPGCLP NFQVFKFIYA
CRLAEMGLAA QAFHYCEVIS RTVLKDPHYY SPVLIGQLIQ MSSQLRLFDP QIKEKPEQES
SIEPSWLVRL RHVDGQIKEG AIAYNTDRST PPPYACSTPS SELDRASQCD GAGVGRDMGP
GAENPLFASL LPNMAQQMQS VQLMPSVPQA VLDGSAAMIP PGDQEPVQSV PFYSVASQSG
PGFAPPGFSN PYGIEPSPVY LGSALPPGGP PQEVEPRTEE QTNLETGMQR IAPDSPSQNS
FPEQREEDFY GRMASMAPGR RSRSASQSSA HMGYGRRSRT TSESSAHSVG RERSNSAANQ
PSPPPSAPAG KETKKETKKE PAPRKTGGNW LRWLMGKGKN EAHLPDDKNK SIVWDEQKQR
WVNLDEPEEE SKPPPPPPTG FPKVPQAVPA GPGGPAGAPV NMFSRRAAGS RARYVDVLNP
GGTKSSGAVP APSDLFAPLA PMPIPANVFV PNSVPGEAQP MEGSGAPEHA PAANQTNADP
AAAAEPEYLN SAVLPPGSGL PVSNPDGSQS GEAAAAPPSG GPAAGTVQFY NPSQFAQSPA
VTGSSRLGRI GQRKYPTLK
//
