ID A0A1V4J7X4_PATFA Unreviewed; 232 AA.
AC A0A1V4J7X4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Interleukin-18 {ECO:0000256|ARBA:ARBA00016740};
GN Name=IL18 {ECO:0000313|EMBL:OPJ68256.1};
GN ORFNames=AV530_013751 {ECO:0000313|EMBL:OPJ68256.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ68256.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ68256.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ68256.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ68256.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the IL-1 family.
CC {ECO:0000256|ARBA:ARBA00010448}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ68256.1}.
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DR EMBL; LSYS01008642; OPJ68256.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4J7X4; -.
DR STRING; 372326.A0A1V4J7X4; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0005125; F:cytokine activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR GO; GO:0010557; P:positive regulation of macromolecule biosynthetic process; IEA:UniProt.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR015529; IL-18.
DR InterPro; IPR000975; IL-1_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR10078; INTERLEUKIN-1 FAMILY MEMBER; 1.
DR PANTHER; PTHR10078:SF35; INTERLEUKIN-18; 1.
DR Pfam; PF00340; IL1; 1.
DR PRINTS; PR01933; INTRLEUKIN18.
DR SUPFAM; SSF50353; Cytokine; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000190648}.
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 232 AA; 26532 MW; 23FB5E167998BBFC CRC64;
MPGRHAGGTA LSLARASPST QPHGTPQPPG FQLRRPRVKM SDEDILVRAV QLGENFCLYF
EGLECDAFCK EKVLHRVLRN VRSQLLVVRP DLDMAAFEDV TDQEMKSGSG MHFNVHYYKT
TTPSAGMPVA FSIQVQDKSY YMCCEKEQGK TIVRFREGEV PKEIPDESNV IFFKKTFTSF
SSRTFKFEYS LEQGMFLAFE DEGYLRKLIL KKLSREDEVD ETMEISLQVK SE
//
