ID A0A1V4J8J0_PATFA Unreviewed; 588 AA.
AC A0A1V4J8J0;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Centrosomal protein of 76 kDa {ECO:0000256|ARBA:ARBA00015706};
GN Name=CEP76 {ECO:0000313|EMBL:OPJ68528.1};
GN ORFNames=AV530_006153 {ECO:0000313|EMBL:OPJ68528.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ68528.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ68528.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ68528.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ68528.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Centrosomal protein involved in regulation of centriole
CC duplication. Required to limit centriole duplication to once per cell
CC cycle by preventing centriole reduplication.
CC {ECO:0000256|ARBA:ARBA00024729}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome, centriole {ECO:0000256|ARBA:ARBA00004114}.
CC -!- SIMILARITY: Belongs to the CEP76 family.
CC {ECO:0000256|ARBA:ARBA00005400}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ68528.1}.
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DR EMBL; LSYS01008581; OPJ68528.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4J8J0; -.
DR STRING; 372326.A0A1V4J8J0; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 3.10.620.30; -; 1.
DR InterPro; IPR028926; CEP76-C2.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR PANTHER; PTHR46436; CENTROSOMAL PROTEIN OF 76 KDA; 1.
DR PANTHER; PTHR46436:SF1; CENTROSOMAL PROTEIN OF 76 KDA; 1.
DR Pfam; PF15627; CEP76-C2; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648}.
FT DOMAIN 102..259
FT /note="CEP76 C2"
FT /evidence="ECO:0000259|Pfam:PF15627"
SQ SEQUENCE 588 AA; 66199 MW; FC6A0A5AF1C01B60 CRC64;
MALPPEKASE LKQIIHQQLV KMDVHGRIRE VLADTIREEL APEHQQLSTE DLIKALRQRG
IIDDVMKELK FVTDVDERER TSAPKPSTHF VDREPPVLRK TNIDPTRRYL YLQVLGGKAF
LEHLQEPEPL PGQICSTFTL CLHFRNQRFR SKPVPCACEP DFHDGFLLEV HKDSLGEGSK
MVDATTMLSI CDPVHMVLIK TDTFGETTLV ASYFLEWRSV LAAENGITNV AVELLGVGTE
SKVSVGVLNV RLEMYPQLNK TLSLEVTNTQ FALERQKTAE KERLFLVYAK QWWREYLQIR
PTHNVRLVKI FAQDENGVNH PVCSYIRPLR AGRLLDTPRQ AARFVSVLGY ERAPVIGGGG
GKQEQWCTLL AFLCRNKGDC EDHANLLCSL LLGFGLEAFV CVGTKAKGVP HTWVMTCGTD
GTVTFWESLT GHRYIHRPIN PDDPPQVEQP KPLYPYRTIG CIFNHQKFFG NCQPTDAVEV
CVFDLHDESK WKPMSGEAIK SVCSPGATSS VPPFPPLCAS TIDAAVTSNE IELQLRILIS
EHRKDLGLST VWDDHLSYLL SPALAAYELE QMPGEHLPLV FGLLFVKK
//
