ID   A0A1V4JE96_PATFA        Unreviewed;       949 AA.
AC   A0A1V4JE96;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Multiple C2 and transmembrane domain-containing protein 2 isoform C {ECO:0000313|EMBL:OPJ70420.1};
GN   Name=MCTP2 {ECO:0000313|EMBL:OPJ70420.1};
GN   ORFNames=AV530_019565 {ECO:0000313|EMBL:OPJ70420.1};
OS   Patagioenas fasciata monilis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX   NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ70420.1, ECO:0000313|Proteomes:UP000190648};
RN   [1] {ECO:0000313|EMBL:OPJ70420.1, ECO:0000313|Proteomes:UP000190648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ70420.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:OPJ70420.1};
RA   Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA   Shapiro B.;
RT   "Band-tailed pigeon sequencing and assembly.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OPJ70420.1}.
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DR   EMBL; LSYS01007908; OPJ70420.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V4JE96; -.
DR   STRING; 372326.A0A1V4JE96; -.
DR   Proteomes; UP000190648; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd04042; C2A_MCTP_PRT; 1.
DR   CDD; cd08376; C2B_MCTP_PRT; 1.
DR   CDD; cd08377; C2C_MCTP_PRT; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 3.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR013583; MCTP_C.
DR   PANTHER; PTHR45911; C2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45911:SF2; MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF00168; C2; 3.
DR   Pfam; PF08372; PRT_C; 1.
DR   SMART; SM00239; C2; 3.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 3.
DR   PROSITE; PS50004; C2; 3.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        762..790
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        866..894
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          227..342
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          382..500
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          534..655
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
SQ   SEQUENCE   949 AA;  107831 MW;  754499E118E986EB CRC64;
     MRGVENNRKG IGSKVSVWLL PYNADTSAWE SLKPFLAGDI TEIPFAAMDL DKPSVWGSLK
     QKTRPFLRNL SVKKTKKRSS KMMERKVHFL DRRLSVSVPD MLEVETLTEE ETTYLNTQVV
     SSCSPKSFSG SVVSLKSRSA SVRPAGEDCL QASQQAMCME VTVTHPDTQI TGSPVSEARR
     ESSADLFELL QSARLSTALS DEGTEYPCGE MDLDSSISSQ IFNDQMALEE ANNCLGDLPS
     PFAYLLTIHL KEGRNLVIRD RCGTSDPYVK FQLNGKTLYK SKVVYKNLNP VWDETVVLPV
     QTLDQKLWIK VYDRDLTSSD FMGSAFVALT ELELNRTTEQ VLKLEDPNSL EDDMGVIVLN
     LSLAVKQGDF KRNRWSSRKK RPSSKSSFMR SMRLSDVLRK NQLWNGLVTI TLLEGKNMPA
     GGLAEIFILL KLGDQRYKSK TLCKSANPQW REQFDFHYFS DRKDMLDIEL FFHINPRQCH
     SRCQVDITAL PMKQTNCLEL PLEKHPGSLL MLVAVAPCTG VSISDLCVCP LGDPSERQQI
     AQRYNIKNSF RDIKDIGFLQ VKVLKAVDLL AADFSGKSDP FCVLELGNDS LQTHTVYKNL
     NPEWNKVFTF PIKDIHDVLE VTVFDEDGDK PPDFLGKVAI PLLSIRNGKQ SCYTLKNKDL
     EHASKGVIYL ELDVLFNPGD RTMPGHFWTD SDHNYLRKEM LVKASIRTFK PREKRFTEEH
     RKFSKKILSR NVDRVKKITM AIWNTIQFLR SCFLWESTVK SVIAFVVFVV TVWSVELYMV
     PLALLLLFAY NFSLITTGRV NNTQDAQDLM GLDEDEDEDD KESEKKGLID RIHMVQEIII
     AVQSILEEMA SFGERIKNTF NWTVPFLSVL ACLVLAAATV ILYFIPLRYI VLIWGINKFT
     KKLRNPYAID NNELLDFLSR VPSDVQKVQH AELKPSSNSS PIRKKRSAL
//