ID A0A1V4JG98_PATFA Unreviewed; 677 AA.
AC A0A1V4JG98;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Coagulation factor XI {ECO:0000313|EMBL:OPJ71196.1};
GN ORFNames=AV530_017449 {ECO:0000313|EMBL:OPJ71196.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ71196.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ71196.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ71196.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ71196.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ71196.1}.
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DR EMBL; LSYS01007721; OPJ71196.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4JG98; -.
DR STRING; 372326.A0A1V4JG98; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd01100; APPLE_Factor_XI_like; 3.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 3.50.4.10; Hepatocyte Growth Factor; 4.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR000177; Apple.
DR InterPro; IPR003609; Pan_app.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24253:SF44; COAGULATION FACTOR XI; 1.
DR PANTHER; PTHR24253; TRANSMEMBRANE PROTEASE SERINE; 1.
DR Pfam; PF00024; PAN_1; 4.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00005; APPLEDOMAIN.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00223; APPLE; 4.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50948; PAN; 3.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Blood coagulation {ECO:0000256|ARBA:ARBA00023084};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hemostasis {ECO:0000256|ARBA:ARBA00022696};
KW Hydrolase {ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|RuleBase:RU363034};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Serine protease {ECO:0000256|RuleBase:RU363034}.
FT DOMAIN 70..153
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 160..243
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 250..333
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 442..677
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 677 AA; 76907 MW; 1F973CBD54E5E3F0 CRC64;
MGFSDPRSVA CGDGKCSLKK QIILSKERQS AKNAEHRPYP FIQICCMFRM IWIYQTFYFI
FLLASVYSEC VTQTYENTYF QGGDLTTVFT PSANYCQVVC TYHPTCLLFT YLPATWTKDP
AKRFSCYLKD SDTEMLPKVD MEGAISGHSL KQCNIQISAC SPDVHIGLDM EGKIYDDTVA
DSYQQCQKRC TNDNRCHFFT YASETFHNAS FRKKCLLKQA SVGTPTSIKM LDEVVSGFSL
KTCQLSEMDC QMDIFEDQEF SGINITSFFT PDISVCQTIC TYFPKCLFFT FFTREWQIES
QRNLCLLKTS TSGIPEALTS RENAVSGFGL LNCRRSFPAC NSRTYMHMNF LGDELNVTYT
KGHRACQQVC TEVIRCQFFT YFSLQDSCNE EGKCECHLRM SSNGSPVKIV HGPGRISGYS
LRLCKKKAST VCMQHSARTI RIVGGTDSAP GEWPWQVSLH VKLSRRRHVC GGSIISNQWI
LTAAHCVMSL ANPNIWHVYA GILKQSEINE DTPFFKVEEI IVHPQYKYAQ TGYDIALMKL
DKPMNFTDLQ LPICLPSKED ANILYTDCWV IGWGYRKEKG RVEDILQKAT VPLMSREECQ
ARYRKRRIGD KVICAGYDEG GRDACKGDSG GPLSCKHEEV WYLVGITSWG EGCARPRQPG
VYTKVAEYSD WIIEKTT
//
