ID A0A1V4JJZ4_PATFA Unreviewed; 678 AA.
AC A0A1V4JJZ4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 08-NOV-2023, entry version 21.
DE SubName: Full=DCC-interacting protein 13-alpha {ECO:0000313|EMBL:OPJ72087.1};
GN Name=APPL1 {ECO:0000313|EMBL:OPJ72087.1};
GN ORFNames=AV530_009390 {ECO:0000313|EMBL:OPJ72087.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ72087.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ72087.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ72087.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ72087.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, ruffle
CC {ECO:0000256|ARBA:ARBA00004466}. Cytoplasmic vesicle, phagosome
CC {ECO:0000256|ARBA:ARBA00004262}. Early endosome membrane
CC {ECO:0000256|ARBA:ARBA00004220}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004220}. Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ72087.1}.
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DR EMBL; LSYS01007300; OPJ72087.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4JJZ4; -.
DR STRING; 372326.A0A1V4JJZ4; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
DR GO; GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
DR GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR CDD; cd13247; BAR-PH_APPL; 1.
DR CDD; cd07631; BAR_APPL1; 1.
DR CDD; cd13158; PTB_APPL; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR047181; DP13A/B.
DR InterPro; IPR037929; DP13A_BAR.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR047236; PH_DP13A/B.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR047237; PTB_APPL.
DR PANTHER; PTHR46415; ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2; 1.
DR PANTHER; PTHR46415:SF3; DCC-INTERACTING PROTEIN 13-ALPHA; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00640; PID; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648}.
FT DOMAIN 277..375
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 500..633
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 398..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 641..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..412
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..490
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 641..663
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..678
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 75797 MW; 074E932F378B1BB4 CRC64;
MPGIDKLPIE ETLEDSPQTR SLLGVFEEDA AAISNYINQL FQAMHRIYDA QNELSAATHL
TSKLLKEYEK QRFPLGGDDE VMTSTLQQFA KVIDELSSCH AVLSTQLADA MMFPITQFKE
RDLKEILTLK EVFQIASNDH DAAITRYGRL SKRRENEKIK AEVIEDVYTS RKKQHQTMMH
YFCALNTLQY KKKIALLEPL LGYMQAQISF FKMGSENLTE QLEEFLTNIG TSVQNVRREM
ECEVENMQQT IEDLEVASDP LYLPDPDTTK FPVHRNLTRK AGYLNARNKT GLVSSSWDRQ
FYFTQGGNLM SQARGDVAGG LVMDIDNCSV MAVDCEDRRY CFQITSFDGK KSSILQAESK
KDYEEWICTI NNISKQIYLS ENPEEIAARV NQSALEAVTP SPSFQQRHES LRPPAQSRPA
AVRTSSTGSL GSESAALSAL SLDSLVAPDT PIQFDIISPV SEDLPGQAKS SGQSGRRTNP
FGESGGSKSE TEDSILHQLF IVRFLGSMEV KSDESPDVVY ETMRQILAAR AIHNIFRMTE
SHLLVTCDCL KLIDPQTQVT RLRFPLPNVV LCAAHQENKR LFGFVLRTSG GRAESRQTSI
CYIFESNNEG EKICDSVGLA KQIALHAELD LEEQSRLIAA SSRANQSSGD GQFVVLSSSQ
SEDSDLGEDG KKKRESEA
//
