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Database: UniProt
Entry: A0A1V4JKJ6_PATFA
LinkDB: A0A1V4JKJ6_PATFA
Original site: A0A1V4JKJ6_PATFA 
ID   A0A1V4JKJ6_PATFA        Unreviewed;      3472 AA.
AC   A0A1V4JKJ6;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   28-FEB-2018, entry version 7.
DE   SubName: Full=Ryanodine receptor 2 isoform D {ECO:0000313|EMBL:OPJ72698.1};
GN   Name=RYR2 {ECO:0000313|EMBL:OPJ72698.1};
GN   ORFNames=AV530_005224 {ECO:0000313|EMBL:OPJ72698.1};
OS   Patagioenas fasciata monilis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae;
OC   Patagioenas.
OX   NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ72698.1, ECO:0000313|Proteomes:UP000190648};
RN   [1] {ECO:0000313|EMBL:OPJ72698.1, ECO:0000313|Proteomes:UP000190648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ72698.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:OPJ72698.1};
RA   Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA   Shapiro B.;
RT   "Band-tailed pigeon sequencing and assembly.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OPJ72698.1}.
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DR   EMBL; LSYS01006902; OPJ72698.1; -; Genomic_DNA.
DR   Proteomes; UP000190648; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 3.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF49899; SSF49899; 3.
DR   SUPFAM; SSF82109; SSF82109; 1.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000190648};
KW   Receptor {ECO:0000313|EMBL:OPJ72698.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN       45     90       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN       98    153       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      159    216       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      224    281       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      484    682       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      898   1095       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1230   1435       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED      345    365       {ECO:0000256|SAM:Coils}.
FT   COILED     2931   2951       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   3472 AA;  393512 MW;  1B018970E9BA95E1 CRC64;
     MYLCCLSTSR SSMDKLAFDV GLQEDTTGEA CWWTIHPASK QRSEGEKVRV GDDLILVSVS
     SERYLHLSYG NGSLHVDAAF QQTLWSVAPI SSGSEAAQGY LIGGDVLRLL HGHMDECLTV
     PSGEHGEEQR RTVHYEGGAV SIHARSLWRL ETLRVAWSGS HIRWGQPFRL RHITTGKYLS
     LLDDKSLLLT DKEKADVKST AFCFRSSKEK LDIGTRKEVD GMGAPEIKYG DSICFIQHVD
     TGLWLTYQSA DAKSVRMGSV QRKAIMHHEG HMDDGLTLSR SQNEESRTAR VIRSTVFLFN
     RFIRGLDALS KKAKSSTVDL PIESVSLSLQ DLIGYFHPPD EHLEHEDKQN RLRALKNRQN
     LFQEEGMINL VLECIDRLNV YSSAAHFADV AGKEAGEAWK SILNSLYELL AALIRGNRKN
     CAQFSGSLDW LISRLERLEA SSGILEVLHC VLVESPEALN IIKEGHIKSI ICLLDKHGRN
     HKVLDVLCSL CVCHGVAVRS NQHLICDNLL PGRDLLLQTR LVNHVSSMRP NIFLGISEGS
     AQYRKWYYEL MVDHLEPFVT AESTHLRVGW ASTEGYSPYP GGGAEWGGNG VGDDLYSYGF
     DGLHLWSGCV ARTVNSPNQH LLRTDDVISC CLDLSAPSIS FRINGQPVQG MFENFNIDGL
     FFPVVSFSAG IKVRFLLGGR HGEFKFLPPP GYAPCFEAVL PKEKLKVEHS REYKQDRSYT
     RDLLGPTISL SQAAFTPVPV DTSQIVLPPH LERIREKLAE NIHELWVMNK IELGWQYGPV
     RDDNKRQHPC LVEFSKLPEQ ERNYNLQMSL ETLKTLLALG CHVGIADEHA EEKVKKMKLP
     KNYQLLSGYK PAPMDLSFIK LTPSQEAMVD KLAENAHNVW ARDRIRQGWT YGIQQDVKNR
     RNPRLVPYAL LDDRTKKSNK DSLREAVRTL LGYGYHLEAP DQDHAMKLDV CSGIMEKFRI
     FRTEKTYAVK TGKWYFEFEA VTAGDMRVGW TRPGCLPDQE LGSDEEAFVF DGFKAQRWHQ
     GNEHFGRSWL AGDVVGCMVD MNEHTMMFTL NGEILLDDSG SELAFKDFEV GDGFLPVCSL
     GPSQVGRMNF GKDVSTLKYF TICGLQEGYE PFAVNTNRDI TIWLSKRLPQ FLPVPQNHEH
     IEVMRIDGTI DSCPCLKVTQ KSFGSQNSKT DVMFFRLSMP IECAEVFSRS AAGGLPGSGL
     FGPKNDLEDY DADSDFEVLM KTAHGHLVPD RTEREKDATK PELNNHKDYV QEKPSRLKQR
     FMLRRTKPDY SMSHSARLTE DVLADDRDDY DYLMQTSTYY YSVRIFPGQE PANVWVGWIT
     SDFHQYDTSF DLDRVRTVTV TLGDEKGKVH ESIKRSNCYM VCAGETMSPG QGRNNNGLEI
     GCLVDAASGL LTFTANGKEL GTYYQVEPST KLFPAVFAQA TSPNVFQFEL GRIKNVMPLS
     AGLFKSEHRN PVSQCPPRLH VQFLTHVLWS RVPNHFLKVD VSRISERQGW MIQCLNPLQF
     MALHIPEENR TIDILELTEQ EELLKFHYHT LRLYSAVCAL GNNRVAHAMC SHVDESQLLY
     AIENKYMPGL LRAGYYDLLI DIHLNTYATA RLMMNNEFIV PMTDETKSIT LFPDENKKHG
     LPGIGLSTSL RPRMQFSSPS FVSISSECFQ FSPEFPLEIL KAKTIEMLTE AVQEGSLHVR
     DPVGGSTEFL FVPLIKLFYT LLIMGIFHNG DLKHILQLIE PRVFKEAMSQ EDEVDFSEKE
     LSSDELKSEE GEEETRREQV PKEGLLQMKL PEPVKLQMCH LLQYLCDCQV RHRIEAIVAF
     SDDFVAKLQE NQRFRYNEVM QALNMSAALT ARKTKEFRSP PQEQINMLLN FKDDKNDCPC
     PEEIRDQLLD FHEDLMAHCG IELDEDGTLD GNSDLTIRGR LLHLMEKVTY LKKKQTEKPV
     DDDDKTSSTL QQLISDTMVR WAQESVIEDP ELVRAMFVLL HRQYDGIGGL VRALPKTYTI
     NSVSVEDTIN LLASLGQIRS LLSVRMGKEE EKLMIRGLGD IMNNKVFYQH PNLMRALGMH
     ETVMEVMVNV LGGGESKEIT FPKMVANCCR FLCYFCRISR QNQKAMFDHL SYLLENSSVG
     LASPSMRGST PLDVAAASVM DNNELALALR EPDLEKVVRY LAGCGLQSCP LLICKGYPDI
     GWNPVEGERY LDFLRFAVFC NGESVEENAN VVVRLLIRRP ECFGPALRGE GGNGLLAAME
     EAIQISEDPT RDGRSPSNGS SKTLEMEEQE DDTIHMGNAI MTFYAALIDL LGRCAPEMHL
     IHAGKGEAIR IRSILRSLIP LEDLVGVISI PFHMPTIAKD GTVVEPDMSA GFCPDHKAAM
     VLFLDRVYGI EDQDFLLHLL EVGFLPDLRA AASLDTAALS ATDMALALNR YLCTAVLPLL
     TRCAPLFAGT EHHASLIDSL LHTVYRLSKG CSLTKAQRDS IEECLLSICG QLRPSMMQHL
     LRRLVFDVPL LNEHAKMPLK LLTNHYERCW KYYCLPGGWG NFGAASEEEL HLSRKLFWGI
     FDALSQKKYE QELFKLALPC LSAVAGALPP DYMESNYVNM MEKQSSMDSD GNFNPQPVDT
     SNITIPEKLE YFINKYAEHS HDKWSMEKFA NGWTYGETYS ESAKVQPLMK QYKLLSEKEK
     EIYRWPIKES LKTMLAWGWR IERTREGDSM ALYNRTRRIS QTSQISVDTA HGYTPRAIDM
     SNVTLSRDLH AMAEMMAENY HNIWAKKKKM ELEAKVGGGN HPLLVPYDTL TAKEKAKDRE
     KAQDILKFLQ INGYVVSRGL KDLELDTPSI EKRFAYSFLQ QLIRYVDEAH QYILEFDGGS
     RGKGEHFPYE QEIKFFAKVV LPLIDQYFKN HRLYFLSAAS RPLSSGGHAS NKEKEMVTSL
     FCKLGVLVRH RISLFGNDAT SIVNCLHILG QTLDARTVMK TGLESVKMAL RAFLDNAAED
     LEKTMENLKQ GQFTHSRNQP KGVTQIINYT TVALLPVLSS LFEHIGQHQF GEDLILEDVQ
     VSCYRILASL YALGTSKSIY VERQRSALGE CLAAFSGAFP VAFLETHLNK HNIYSIYNTK
     NARDRAVLNL PTSVEEVCPN IPSLVKLMEE IVELAESGIR YTQMPHIMEV ILPMLCSYMS
     HWWEHGPENN PDKAEMCCTA LTSEHMNTLL GNILKIIYNN LGIDEGAWMK RLAVFSQPII
     SKVKPQLLKT HFLPLMDKLK KKAAVVVSDE EHLRAEGRGD MSEAELLILD EFTTLARDLY
     AFYPLLIRFV DYNRAKWLKE PNPEAEELFR MVAEVFIYWS KSHNFKREEQ NFVVQNEINN
     MSFLISDTKS KMSKAAVSDQ ERKKMKRKGD RYSMQTSLIV AALKRLLPIG LNICAPGDQE
     LIALAKNRFS MKDTEDEVRD IIRSNLHLQG KLEDPAIRWQ MALYKDLPNR TEDSSDPEKT
     VERVLDIANV LFHLEQRSAC VGRGYFFWES IESFITVCEA ITNYLTSTFW FA
//
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