ID A0A1V4JKK0_PATFA Unreviewed; 715 AA.
AC A0A1V4JKK0;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Prospero homeobox protein 1 isoform A {ECO:0000313|EMBL:OPJ72287.1};
GN Name=PROX1 {ECO:0000313|EMBL:OPJ72287.1};
GN ORFNames=AV530_018743 {ECO:0000313|EMBL:OPJ72287.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ72287.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ72287.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ72287.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ72287.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ72287.1}.
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DR EMBL; LSYS01007194; OPJ72287.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4JKK0; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0007399; P:nervous system development; IEA:UniProt.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.500; Homeo-prospero domain; 1.
DR InterPro; IPR023082; Homeo_prospero_dom.
DR InterPro; IPR037131; Homeo_prospero_dom_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR039350; Prospero_homeodomain.
DR PANTHER; PTHR12198; HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26; 1.
DR PANTHER; PTHR12198:SF6; PROSPERO HOMEOBOX PROTEIN 1; 1.
DR Pfam; PF05044; HPD; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51818; HOMEO_PROSPERO; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:OPJ72287.1};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000313|EMBL:OPJ72287.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 576..715
FT /note="Prospero"
FT /evidence="ECO:0000259|PROSITE:PS51818"
FT REGION 103..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 261..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 499..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 222..256
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 103..145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..297
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 80474 MW; BDF0C2D231360700 CRC64;
MPDHDSTALL SRQTKRRRVD IGVKRTVGTA SAFFAKARAT FFSAMNPQGS EQDVEYSVVQ
HADGEKSNVL RKLLKRANSY EDAMMPFPGA TIISQLLKNN MNKNGGTEPS FQASGLSSTG
SEVHQEDVCS NSSRDSPQEC LSPFGRPTMS QFDVDRLCDE HLRAKRARVE NIIRGMSHSP
SVALRGSENE REIAPQSVSP RESYRENKRK QKLPQQQQQS FQQLVSARKE QKREERRQLK
QQLEDMQKQL RQLQEKFYQI YDSTDSENDE DGNLSEDSMR SETMDARAGD SVSRSDNEMC
ELDPGQFIDR ARALIREQEI AENKPKREGP KEKEQGPNAF HPEGKHLAET LKQELNTAMS
QVVDTVVKVF SSKPSRQLPQ VFPPLQIPQA RFAVNGENHN FHTANQRLQC FGDVIIPNPL
DTFGSVPMPG ATDQTEALPL VVRKNSSDQS ASAPPAGGHH ASLHQSPLSA TAGFSTSSFR
HPFPLPLMAY PFQSPLGAPS ASFPGKERAS PESLDLTRET TSLRTKMSSH HMNHHPCSPA
HPPSAAEGLS LSLIKSECGD LQDMSEISPY SGSAMQEGLS PNHLKKAKLM FFYTRYPSSN
MLKTYFSDVK FNRCITSQLI KWFSNFREFY YIQMEKYARQ AINDGVTSTE ELSITRDCEL
YRALNMHYNK ANDFEQVPER FLEVAQITLR EFFNAIIAGK DVDPSWKKAI YKVIC
//
