ID A0A1V4JMF4_PATFA Unreviewed; 924 AA.
AC A0A1V4JMF4;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Interphotoreceptor matrix proteoglycan 1 {ECO:0000256|ARBA:ARBA00040753};
DE AltName: Full=Sialoprotein associated with cones and rods {ECO:0000256|ARBA:ARBA00042018};
GN Name=IMPG1 {ECO:0000313|EMBL:OPJ73371.1};
GN ORFNames=AV530_005743 {ECO:0000313|EMBL:OPJ73371.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ73371.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ73371.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ73371.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ73371.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, photoreceptor outer
CC segment {ECO:0000256|ARBA:ARBA00004504}. Photoreceptor inner segment
CC {ECO:0000256|ARBA:ARBA00004437}. Secreted, extracellular space,
CC extracellular matrix, interphotoreceptor matrix
CC {ECO:0000256|ARBA:ARBA00004593}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ73371.1}.
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DR EMBL; LSYS01006902; OPJ73371.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4JMF4; -.
DR STRING; 372326.A0A1V4JMF4; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0033165; C:interphotoreceptor matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0001917; C:photoreceptor inner segment; IEA:UniProtKB-SubCell.
DR GO; GO:0001750; C:photoreceptor outer segment; IEA:UniProtKB-SubCell.
DR GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR GO; GO:0005540; F:hyaluronic acid binding; IEA:UniProtKB-KW.
DR GO; GO:0007601; P:visual perception; IEA:InterPro.
DR Gene3D; 3.30.70.960; SEA domain; 2.
DR InterPro; IPR039861; IMPG.
DR InterPro; IPR000082; SEA_dom.
DR InterPro; IPR036364; SEA_dom_sf.
DR PANTHER; PTHR12199; INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN; 1.
DR PANTHER; PTHR12199:SF3; INTERPHOTORECEPTOR MATRIX PROTEOGLYCAN 1; 1.
DR Pfam; PF01390; SEA; 2.
DR SMART; SM00200; SEA; 2.
DR SUPFAM; SSF82671; SEA domain; 2.
DR PROSITE; PS50024; SEA; 2.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00022981};
KW Heparin-binding {ECO:0000256|ARBA:ARBA00022674};
KW Hyaluronic acid {ECO:0000256|ARBA:ARBA00023290};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:OPJ73371.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Sialic acid {ECO:0000256|ARBA:ARBA00022981};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..924
FT /note="Interphotoreceptor matrix proteoglycan 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012415092"
FT DOMAIN 231..349
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 731..844
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT REGION 164..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..180
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 924 AA; 101973 MW; 54E38320EA793E10 CRC64;
MHLKTGLIFF IICLALQVQG SREIPNKINR GEAKHLADAS GSDKTERTTK RSRVSTIRRI
FDMAKHRTKR SPFFSTGVKV CPQESVKQIL ASHQAYYRLR VCQEVVWEAF RIFLDRIPDT
AEYQNWVTAC QRETFCIFDI GKNFSNSQEH LEIIQRRVKH RTFQERKDEI STEKTGGKKV
EDIPSISTGS PGTSLSPYAP APNGTLLNEI VNDTKTPVKE PGTNTVPELP VEQMVEFSVT
LTDQEYTAEL SDPDSPQYRQ LAAKFQLQMQ KIFEKLPGFK EIHVLGFKSS STIARYVVNF
ERDASEIKST ADAISTIGSN KVENEKLPLS PKEEQEISAT KLTVTDLQQL VAIALHEDQS
LPMDLGTLQF TDEAIIPPSD FDNDIQGMVT IPLAGPDLED SMSVELPLGY PSPATVDQTG
AISINEFTTG IPMLSGEISA PEDFNNFVSS EPVFPTKPFR EPFQDKYPPD TEDIATDYQS
FTVPFNALGS TSSPPKTEDS YLPPPADDSA GNELITDGYR SPTEQPTTLV VYTTDSFTPP
NLLQARDETN EAEEKKELTD VTVPPFKVAD QDSLSGQAVK IVDESESSGN DILVTASTYE
MLPFFIGSSD LSTTQPEDVI TGVLPLDQTA PQPAATSPSY SQSQIIEQSL EVSDPSLPAS
EIVSPDDTGI GVQDIAAELD HVSVMSTTAL DEVEHGSGYI SVVTTEPAKA TPAPTLKYVT
TSSMTTAAKG KELVVFFSLR VTNMHFSDDL FNRSSTEYKA LEQQFMQLLL PYLQSNLTGF
KQLEILNFRN GSVIVNSKMK FARTVPYNIT EAVHCVLEDF CDAAAQLLNL EIDSYSLDIE
PADQADPCKF MACDEFSECI MNEWTKEADC LCKPGYASQD GLPCRSLCEL EPHLCVNGGK
CELVPGRGAV CRSPDQFTKP RLTI
//
