ID A0A1V4JPC3_PATFA Unreviewed; 220 AA.
AC A0A1V4JPC3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE Short=FGF {ECO:0000256|RuleBase:RU049442};
GN Name=FGF19 {ECO:0000313|EMBL:OPJ74038.1};
GN ORFNames=AV530_013426 {ECO:0000313|EMBL:OPJ74038.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ74038.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ74038.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ74038.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ74038.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ74038.1}.
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DR EMBL; LSYS01006880; OPJ74038.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4JPC3; -.
DR STRING; 372326.A0A1V4JPC3; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0005104; F:fibroblast growth factor receptor binding; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IEA:InterPro.
DR GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR035444; FGF15/19/21.
DR InterPro; IPR002209; Fibroblast_GF_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR PANTHER; PTHR11486:SF74; FIBROBLAST GROWTH FACTOR 19; 1.
DR Pfam; PF00167; FGF; 1.
DR PIRSF; PIRSF037961; FGF-19_FGF-21; 1.
DR PRINTS; PR00263; HBGFFGF.
DR PRINTS; PR00262; IL1HBGF.
DR SMART; SM00442; FGF; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
DR PROSITE; PS00247; HBGF_FGF; 1.
PE 3: Inferred from homology;
KW Mitogen {ECO:0000256|ARBA:ARBA00023246};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Signal {ECO:0000256|RuleBase:RU049442}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|RuleBase:RU049442"
FT CHAIN 21..220
FT /note="Fibroblast growth factor"
FT /evidence="ECO:0000256|RuleBase:RU049442"
FT /id="PRO_5011812484"
FT REGION 191..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 220 AA; 24151 MW; 27E682260934948D CRC64;
MEPRPVALAL LSLAAAAVTA VSLPLPDAGP HVNYGWGEPI RLRHLYTASK HGLFSCFLRI
GGDGRVDAAG SQSPQSLLEI RAVAVRTVAI KGVRSSRYLC MDEAGRLHGQ LRYSTEDCSF
EEEIRPDGYN VYKSKKYGIS VSLSSAKQRQ QYKGKDFLPL SHFLPMINTV PVESSDFGEY
SDYSQALEPE VYSSPLETDS MDPFGITSKL SPVKSPSFQK
//
