ID A0A1V4JPX7_PATFA Unreviewed; 417 AA.
AC A0A1V4JPX7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Tumor necrosis factor receptor superfamily member 6 {ECO:0000256|ARBA:ARBA00015761};
DE AltName: Full=Apo-1 antigen {ECO:0000256|ARBA:ARBA00032338};
DE AltName: Full=Apoptosis-mediating surface antigen FAS {ECO:0000256|ARBA:ARBA00032502};
DE AltName: Full=FASLG receptor {ECO:0000256|ARBA:ARBA00030181};
GN ORFNames=AV530_013256 {ECO:0000313|EMBL:OPJ73807.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ73807.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ73807.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ73807.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ73807.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane raft {ECO:0000256|ARBA:ARBA00004285}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ73807.1}.
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DR EMBL; LSYS01006880; OPJ73807.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4JPX7; -.
DR STRING; 372326.A0A1V4JPX7; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd10580; TNFRSF10; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR008063; Fas_rcpt.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR034024; TNFRSF10_N.
DR PANTHER; PTHR46874; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6; 1.
DR PANTHER; PTHR46874:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6; 1.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR PRINTS; PR01680; TNFACTORR6.
DR SMART; SM00208; TNFR; 3.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..417
FT /note="Tumor necrosis factor receptor superfamily member 6"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013319566"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 61..102
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 61..102
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 345..393
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT REGION 209..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 81..94
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 84..102
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 417 AA; 46056 MW; DB35526F2F349DB8 CRC64;
MGAGGVARLL LVTLLIVPAT GAEDCGEGEY LHEGRCCVFC PAGTYVDQHC SAPHLRGTCL
PCIEGEGYTA HENGLEECLL CRQCKDDQIT LRPCTLMRDT ECQCKPGYFC PAEGCEVCQR
CSTVYLEGKE TVQNCNATTG PGYDLPDQGS TALAWSIVIG LGCGVLVLVF VVRKLKSDKA
PSTVKDVEKG LELEGSTESL ILPEVEAPAN KAAKPEGGNC GESPEGEAQT NVNLEVNNTS
PEENGGVLSQ RAAILRGGLR RHVGRFWRRI TMSSLPAKTG HNPGFHQNAQ SNIQSGRMPA
NLMAREPKFR IIVKDLSQKE LRDSFGAFIN EVPPNKWKRL MRTHLQENDI TKIIYDFPKD
REEQYYQMLL TWKNTLGEKQ CIIKLLDELR YLDTKAYDNI LNTLKSNNII TKIEATD
//
