ID A0A1V4JRI9_PATFA Unreviewed; 2087 AA.
AC A0A1V4JRI9;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=DEP domain-containing protein 5 isoform C {ECO:0000313|EMBL:OPJ74783.1};
GN Name=DEPDC5 {ECO:0000313|EMBL:OPJ74783.1};
GN ORFNames=AV530_018308 {ECO:0000313|EMBL:OPJ74783.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ74783.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ74783.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ74783.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ74783.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ74783.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LSYS01006629; OPJ74783.1; -; Genomic_DNA.
DR STRING; 372326.A0A1V4JRI9; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd04449; DEP_DEPDC5-like; 1.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR045838; DEPDC5_CTD.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR027244; IML1.
DR InterPro; IPR048255; IML1_N.
DR InterPro; IPR031701; SIX1_SD.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR13179; DEP DOMAIN CONTAINING PROTEIN 5; 1.
DR PANTHER; PTHR13179:SF8; GATOR COMPLEX PROTEIN DEPDC5; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF19418; DEPDC5_CTD; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF12257; IML1; 1.
DR Pfam; PF16878; SIX1_SD; 1.
DR SMART; SM00049; DEP; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000190648}.
FT DOMAIN 1201..1276
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 1744..1800
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 1746..1801
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 513..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1123..1162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2087 AA; 235174 MW; D8F2EB836C3A0001 CRC64;
MRKWRAKPEG PRRDCAAAVG GGLGTGRLDM QDMRTNKVYK LVIHKKGFGG SDDELVVNPK
VFLQIKLGDV VEIAHPNDEY SPLLLQVKSL KEDLQKETIS VDQTVAQVFR LRPYQDVHVN
VVDPKEVTLD LVELTFKDQY IGRGDMWRLK KSLVSTCAYV TQKVEFAGIR AQAGELWVKN
EKVTCGYISE DTRVVFRSTS AMVYIFIQMS CEMWDFDIYG DLYFEKAVNG FLADLFTKWK
EKNCSHEVTV VLFSRTFYEA KSIDEFPETH RASIRQDHEG RFYEDFYKVV VQNERREEWT
SLLVTIKKLF IQYPVLVRLE QAEGFPPGYN STSAQGNYLE AINLSFNVFD KHYINRNFDR
TGQMSVVITP GVGVFEVDRL LMILTKQRMI DNGIGVDLVC MGEQPLHAVP LFKLHNRCGP
GDSRLCDDYN IPHWINHSFY TSKSQLLCNS FTPRIKLAGR KPLTEKAKNN RDASLGAPKD
AENALPIQVD YDGYDAQVFR LPGPSRAQRC TTFRSVRERE SRTRKSSSSY DVSCSPSLQS
RTLPSEEVRS QASDDSSLGK ISNILMIPRP HLHQCEVSSS LGYTSTRDVL ESMLESQQRD
SSAPGRFHVG SAESMLHIRP GGYTPQRALI NPFAPSRMPM KLTSNRRRWM HTFPVGPSGE
AIQIHHQTRQ NMAEMQGSGQ QDLTHSSAEL LELAYHEATG RHVSSRHPGD GASFLSFSGT
EEFSSGPAGG NGAGMNVKTQ NKDSLEDAVS NSPDPMPGFC CTVGVDWKSL TTPACLPLTT
DYFPDRQSLQ NDYTEGCYDL LPEADMDRRD EEGVQMTAQQ VFEEFICQRL MQGYQIIVQS
KPQKPATTVP PPLSSSPLYS RGLVSRNRPE EEDQYWLSMG RTFHKVTLKD KIITVTRYLP
KYPYESAQIN YTYSLCPSHS DSEFVSCWVE FSHERLEEYK WNYLDQYICS AGSEDFRQLC
RTLSCLTSSI SLIESLKFWR TRFLLLPACI SATKRIMEGE VHCDVYGDKP RSDEEEWQLL
DGFIRFVEGL NRIRRRHRSD RMIRKGSAMK GLQIAGPIPT HSLDQQPGPP IGKKGTSALS
ALLQMEASQK TLGEQQAAML AGKSSGPSES GSIAITPTYM DSPRKVSVDQ SVPATSESNT
LINQGQLPDR GNAQTLGSSQ SIADQGYPTA AAAEAGSQQC SASTLTSSST LIEILEAMKH
PTTGIQLLSE QKGLSPYCFI SAEVVHWLVN NVEGVQTQAM AIDIMQKMLE EQLIVHASGE
ALRTFIYGFY FYKIVMDKEP DRVGMQQPAM WHTAAVDDFS AFQRKWFEVA FVAEELLHSE
IPAFFLPWLP SRPASYASRH SSFSRSFGGR SQAAALLAAT VPEQRTVTLD VDVNNRTDRL
EWCSCYYHGN FSLNAAFEIK LHWMAVTAAV LFEMVQGWHR KATSCGFLLV PVLEGPFALP
SYLYGDPLRA QLFIPLNVSC LLKEGSEHLF DGFEPETYWD RMHLLQEAIA YRFGFVQDKY
SASAFNFPAE NKPQYIHVTG TVFLQLPYSK RKFSCGQQRR RRNSTSSTNQ NMFCEERIGY
NWAYNTMLTK TWRSSATGDE KFADRSWSRK APSALPTGKG FQQDVRMKRF MAMLNRNRNK
DPPPAKLLDL AGQLCQDLQS SPPSLEKLVE AMMGCEHKMY FLTNIHVVRA CVSFHIHNGQ
HDTACRLLEY CKAEEKEELV QLWHEIHYRR VMEKHHMNFL TPLQKFRCRK RNPPPISLCP
EGLKNRNYSD EVRQQLHRFA AEVTANPSKE QREGLARDMN LQPTQVYNWF ANYRRRQKSS
LLRTEKLNNS CPERTLTYHK KEQQDKGSCA PQTADGSCVG IGPEQMEITL MPCDPGWEQS
AADLDKPPEG TYLKMLESSF MQSSELFEAR TSKALTTHDA EQPIAFCTGA MLEPGTCFNS
AVLQPREVAS STDASPQLGN FVLCSCGSLT FPDERLDVWQ APCSTRGVSG SVWTPSIEGI
RAPLSRVPQG GCIEASSGRI IQQSDLELES FILREGQLGT LESILPHSSC QTVFGRPQCP
PVSAPCMEES QALGQSQVLE YPAGDPLAND TFWAAWLLFE FSAGARM
//
