ID A0A1V4JRQ7_PATFA Unreviewed; 614 AA.
AC A0A1V4JRQ7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 22-FEB-2023, entry version 17.
DE SubName: Full=Microprocessor complex subunit DGCR8 isoform B {ECO:0000313|EMBL:OPJ74888.1};
GN Name=DGCR8 {ECO:0000313|EMBL:OPJ74888.1};
GN ORFNames=AV530_018394 {ECO:0000313|EMBL:OPJ74888.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ74888.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ74888.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ74888.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ74888.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ74888.1}.
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DR EMBL; LSYS01006629; OPJ74888.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4JRQ7; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0070877; C:microprocessor complex; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0031053; P:primary miRNA processing; IEA:InterPro.
DR CDD; cd19867; DSRM_DGCR8_rpt1; 1.
DR CDD; cd19868; DSRM_DGCR8_rpt2; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 3.30.160.590; -; 1.
DR InterPro; IPR040375; DGCR8.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR13482:SF3; MICROPROCESSOR COMPLEX SUBUNIT DGCR8; 1.
DR PANTHER; PTHR13482; MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8; 1.
DR Pfam; PF00035; dsrm; 2.
DR SMART; SM00358; DSRM; 2.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50137; DS_RBD; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 142..175
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 352..419
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..25
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 614 AA; 69825 MW; 48DE41D9E54F837B CRC64;
MNVESHTCPP PLPPNEQPPP PPLQTSSDAE EKRVEYAVLD ELEDFTDNLM EIDEEGGGFT
SKAIVQRDKV DEETLNYSYE DDFDNDVDAL LEEGLRAPKT RRVENEKYGG ESDHQSDGET
TVQPMMTKIK TVLKSRGRPP TEPLPDGWIM TFHNSGIPVY LHRESRVVTW SRPYFLGTGS
IRKHDPPLSS IPCLHYKKMK ENEEREQNND ITPNGEVSPV KHLDKSSELD CQTEEPDSTA
ADSGPLDDKD TSGGDAAQGA LGQVKAKVEV CKDESVDLED FRRYLEKRFD FEQVTVKKFR
TWAERRQFNR EMKRKQAESE RPILPANQKL ITLSVQDAPT KKEFVINPNG KSEVCILHEY
MQRVLKVRPV YNFFECENPS EPFGASVIID GVTYGAGTAS SKKLAKNKAA RATLEILIPD
FVKQTSEEKP KDSEELEYFN HISIEDSRVY ELTSKAGLLS PYQILHECLK RNHGMGDTSI
KFEVIPGKNQ KSEYVMTCGK HTVRGWCKNK RVGKQLASQK ILQLLHPHVK NWGSLLRMYG
RESSKMVKQE TSDKSVIELQ QYAKKNKPNL HILNKLQEEM KKLAQEREET RKKPKMTIVE
SAQPGSEPLC TVDV
//
