ID A0A1V4JTK3_PATFA Unreviewed; 1498 AA.
AC A0A1V4JTK3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN ORFNames=AV530_019840 {ECO:0000313|EMBL:OPJ75434.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ75434.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ75434.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ75434.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ75434.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620; EC=3.1.3.48;
CC Evidence={ECO:0000256|ARBA:ARBA00001490};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ75434.1}.
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DR EMBL; LSYS01006356; OPJ75434.1; -; Genomic_DNA.
DR STRING; 372326.A0A1V4JTK3; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd00047; PTPc; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR19134:SF554; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR PANTHER; PTHR19134; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE; 1.
DR Pfam; PF00102; Y_phosphatase; 2.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 2.
DR SMART; SM00404; PTPc_motif; 2.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 2.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 2.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Receptor {ECO:0000313|EMBL:OPJ75434.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1498
FT /note="protein-tyrosine-phosphatase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013002798"
FT TRANSMEM 851..873
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 609..707
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 939..1192
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 1108..1183
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT DOMAIN 1224..1487
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 1406..1478
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 1498 AA; 170033 MW; 9E6D10695D3A90B2 CRC64;
MDLRWTFPLV LMFLLAVTEQ EEPDLHVSGE PLETERCQQP QWDSRLHFTP NHSFYGLNEE
VTLSCFVEDS PPLAVIRCAK GMTPGWKNVW EVKDNKDMWH EVAESLTCTT GKCPKPQWDE
RLRFSSSRRI YRQNEELNLT CPGALKPSLP KVKCARQFLR VSSGEPVYGD NWWGRNSTGA
WIPIERAPEC IEMCQRPQWD TRLELTPDQK NYKKNEEVML RCPEGLQLSF TKIKCSVIVQ
HDSNGKPVYR EYWYGIGIYD STSIPSNVEC LETCQKPQWD TKLQLSPNQW NYRKNEEVML
SCMAGLQPSF TKIKCSSEDQ HNISEKPVYR GVWHGMDSSG GWIPIQSGVE CLETCQRPRW
DTRLRLVPDQ ENYKKNDQVT LSCPQGFQPS VTRIKCSSNV QPISSWNSPH WSGWDSRRVW
IHVVSSVKCI EMCQRPQWDT NLQLEPDQEN YEKNKQVMLS CPEGFQTPFT HVKCTRAFQP
TSNGQPVYTD RWLGKDSRDT WIRIQSSVQC IGILQVVPGT LEISSTSIKL NWTCSLPDVC
QRMRARCRLA GPSSSPCEAE EVKGEETLQG QEGTFTCPTL QPFTDYSVTI SLPPNMILYM
QLFRTSEAVP DKLEKLWLEP SNGSLMWKPL PSCKGEIIGY QLNITTRSTQ DGSLLEMERL
WLNIPVTEYR LPEHSPGSRY VVMIQGLTAA GAGAASLWEL QTNSSDTPHP LDITCHSIRD
ISPSQGTAVL PLHPIARPSE AVREHQLIVA VMDNVTSVEG ACLGEPQPFN TSQQPGAYVA
AVLNLTAPTE FVLGNGTHGQ GYHNAALHPG WDYMALLRLV RRSQQAEKFS CICYSFSVGP
EPVPRLGRMS VLLAVLLVTA LLALGILLLF VLLRRKYNSS KTSENNSVIP LRKHQGGVGK
LNTQIPVEEL LEALKRFKRA EIEAEQTEDE SLDRHGAGRL REYQQLSSTL LHPCDAGKEL
CNQNKNRYKS IIPYDHCRVV LQHSDTENGY INASYVDSYR SPRFFIAAQG PLPGTVVDFW
QMVWQEKTSV IVMLTGLVEQ NKTKCEQYWP EQEQVYGDFT VTLNNTRTTT GLVTRIFCLQ
KAGCALPRVV EQFHYLLWPD HGVPRNPAQL LCLVEVVNKR ALEAPGGPVL VHCSAGIGRT
GTFIALDFLL KMGKAERKVD VFHCVQKLRE QRVSMVQTKE QYTFLYEVLL EGLLCGNTGV
PVESITSHVH CLREAETSRH NNVLEKEFKA LQKFSELFQL LPCREAEKPS NQPKNRKPGI
LPADSCRPIL MSSLNADGSP GYINAVFAST YTKEDRLIIT QLPFATTLVD FWALIWDYTC
TSVVVLNQLQ ELDQTYVEFW PTQDEATYGR FHVLLISEKP GDGFTTWTLA LTNKQQPKKS
ALQVQFWQLT DWPMQQRLPP HPTTIISLLG KVETNHRQSQ DGHILVTCWD GASRSGIFCA
TGFLCEQIQS EGLVDVSQAV RMLKRRRRQL IKDVEQYGLC YELALSYLNS FETYGNFK
//
