ID A0A1V4JZE5_PATFA Unreviewed; 406 AA.
AC A0A1V4JZE5;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 08-NOV-2023, entry version 17.
DE SubName: Full=Bone morphogenetic protein 4 {ECO:0000313|EMBL:OPJ77579.1};
GN ORFNames=AV530_004708 {ECO:0000313|EMBL:OPJ77579.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ77579.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ77579.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ77579.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ77579.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ77579.1}.
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DR EMBL; LSYS01005376; OPJ77579.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4JZE5; -.
DR STRING; 372326.A0A1V4JZE5; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13765; TGF_beta_ADMP; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF241; ANTI-DORSALIZING MORPHOGENETIC PROTEIN; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 293..406
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 406 AA; 44598 MW; 966AA8F5B7CB286C CRC64;
MAHLKGKEAV RVINAALGRQ EEWSWSRDSR AMLGTILLLL ALAKPASPSP ASAASRRAEA
LKKLLEVFGM EDPPPPPTHS KQPPQYMVDL FNTVANADGV TKNPDILEGN TVRSFLDKTH
GEKMRFLFVL SSVGKNEKIL TAELHLFRLW PRATEGPKRH HLCQVSVYQV LEQSETDAPG
GKKLLAARLV PLQGSGWEVF AITQAVRDWT EDESSNQGLL VTVQGLGGSP LEPSPLQFAS
GKDHHESKKP MLVLFTDDGR RGASQPAVGF PDLQPQTPAL PAKMLAPRVA GSRRTRSLDR
LQPCQRHPLS VDFEEIGWSG WIISPRGYNA YHCKGSCPFP LGENMRPTNH ATVQSIINAL
KLSEGVSSPC CVPDKLYSIN LLYFDDDENV VLKQYDDMVA GSCGCH
//
