ID A0A1V4JZQ3_PATFA Unreviewed; 759 AA.
AC A0A1V4JZQ3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Ribosome biogenesis protein BOP1 {ECO:0000256|HAMAP-Rule:MF_03027};
DE AltName: Full=Block of proliferation 1 protein {ECO:0000256|HAMAP-Rule:MF_03027};
GN Name=BOP1 {ECO:0000256|HAMAP-Rule:MF_03027,
GN ECO:0000313|EMBL:OPJ77595.1};
GN ORFNames=AV530_008741 {ECO:0000313|EMBL:OPJ77595.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ77595.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ77595.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ77595.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ77595.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the PeBoW complex, which is required for
CC maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S
CC ribosome. {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- SUBUNIT: Component of the PeBoW complex, composed of BOP1, PES1 and
CC WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and
CC WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
CC {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|HAMAP-
CC Rule:MF_03027}. Nucleus, nucleoplasm {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|RuleBase:RU004020}.
CC -!- SIMILARITY: Belongs to the WD repeat BOP1/ERB1 family.
CC {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ77595.1}.
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DR EMBL; LSYS01005359; OPJ77595.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4JZQ3; -.
DR STRING; 372326.A0A1V4JZQ3; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR HAMAP; MF_03027; BOP1; 1.
DR InterPro; IPR028598; BOP1/Erb1.
DR InterPro; IPR012953; BOP1_N_dom.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR17605:SF0; RIBOSOME BIOGENESIS PROTEIN BOP1; 1.
DR PANTHER; PTHR17605; RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN; 1.
DR Pfam; PF08145; BOP1NT; 1.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00056; HSFDOMAIN.
DR SMART; SM01035; BOP1NT; 1.
DR SMART; SM00415; HSF; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00434; HSF_DOMAIN; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|HAMAP-Rule:MF_03027};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517, ECO:0000256|HAMAP-
KW Rule:MF_03027};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552, ECO:0000256|HAMAP-
KW Rule:MF_03027};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 36..60
FT /note="HSF-type DNA-binding"
FT /evidence="ECO:0000259|PROSITE:PS00434"
FT REPEAT 422..463
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 759 AA; 87572 MW; 2106792224798607 CRC64;
MRGWKRRGGI RRQRLRAQSG NSFHVFDQGQ FAKEVLPKYF KHNNMASFVR QLNMYGFRKV
VHIEQGGLVK PEKDDTEFQH PYFIRGQEHL LENIKRKVTS VSSIKNEDIK VRQDNVTKLL
TDIQVMKGKQ ESMDSKLMAM KQYDIRNTVG NIPMEWYQDF PHIGYNLDGK KIYKPIRNKD
ELDMFLEKME NPEYWRTVQD KMTGADIKLT DEQVELVHRL QRGQFGDVHF DPYEPAVDFF
THEVMIHPVT NRPADKRSFI PSLIEKEKVS KLVHAIKMGW IKPRKPKDDT PTYYDLWAHE
DPNSILGRHK MHVPAPKMKL PGHEESYNPP PEYLLSEEEK LAWEQQEPAE RKLNFVPQQH
RCLRAVPAYP RFIHERFERC LDLYLCPRQR KMRVNVDPED LIPKLPKPRD LQPFPTTQAL
IYRGHSSLVR CLSVSPSGQW LVSGSDDGTV RFWEVCTARC MKTLPVGGVV KSVAWNPNPT
VCLVAVAVEQ SVLLVNPCLG DKLLYGATDQ LLESYAAPEE ERVQPVQWVP ATAEQHGKGV
RLLVQHSKAV KQVTWHGKGD YFASVVSDNS NMQVLIHQTS KRWSQNPFRK SKGLVQCVLF
HPIRPYFFVA TQRYVRVYNL LKQELTKKLM TNCKWVSSMA IHPGGDNIIC GSYDSKLAWF
DLDLSTRPYQ LLRHHKKALR SVAFHKRYPL FASASDDGTV IVCHGMVYND LLQNPLLVPV
KVLKGHAPTL DLGVLAVLFH PTQPWVFSSG ADGTVRLYT
//
