ID A0A1V4K466_PATFA Unreviewed; 714 AA.
AC A0A1V4K466;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Rab5 GDP/GTP exchange factor isoform C {ECO:0000313|EMBL:OPJ78677.1};
GN Name=RABGEF1 {ECO:0000313|EMBL:OPJ78677.1};
GN ORFNames=AV530_003456 {ECO:0000313|EMBL:OPJ78677.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ78677.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ78677.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ78677.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ78677.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ78677.1}.
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DR EMBL; LSYS01005108; OPJ78677.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4K466; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd18366; BTB_POZ_KCTD7; 1.
DR Gene3D; 1.10.246.120; -; 1.
DR Gene3D; 1.20.1050.80; VPS9 domain; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR041545; DUF5601.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR003123; VPS9.
DR InterPro; IPR045046; Vps9-like.
DR InterPro; IPR037191; VPS9_dom_sf.
DR PANTHER; PTHR23101; RAB GDP/GTP EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23101:SF122; RAB5 GDP_GTP EXCHANGE FACTOR; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF18151; DUF5601; 1.
DR Pfam; PF02204; VPS9; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00167; VPS9; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF109993; VPS9 domain; 1.
DR PROSITE; PS51205; VPS9; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000190648}.
FT DOMAIN 455..598
FT /note="VPS9"
FT /evidence="ECO:0000259|PROSITE:PS51205"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 714 AA; 82597 MW; 066A40EF34FCCAAE CRC64;
MNIKKQHCHG CRPSRPADES QRDGGSYGAE QRQALPLLPQ QFPEVVPLNV GGMYFTTRLS
TLRRYEDTML AAMFSGRHYI PTDAEGRYFI DRDGTYFGDI LNFLRSGDLP PRERVRSVYK
EAQYYSIGPL LDNLEDVQPL KGEKVRQAFL GLMPYYKDHL ERIIEIAKLR AMQRKARFAK
LKVCVFKEEM PITPYECPHF NSLRFERSES ETKLFEHHCE VDVSFGPWEA VADVYDLLHC
IVTDLSDRGI TVDHQCIGVC DKHLINHYYC KRPIYEFKIT WWLQREEEEA YASSQSTQGA
QSLTFSKFEE KKTNEKTRKV TTVKKFFTAS SRTGAKKAEI QEAKAPSPSI NRQASIETDR
VSKEFIEFLK TYHKPGQDIY KQCKLFLDTM NHKRDLSIEE QSECAQDFYQ NVAEKLQTRW
KAPPEKVEKA MDQIEKYIMT RQYKYVFCPE TTDDEKKDLA VQKRIRALHW VTPQMLCVPV
NEEIPEVSDM VVKAITDIIE MDSKRVPRDK LACITKCSKH IFNAIKITKN EPASADDFLP
TLIYIVLKGN PPRLQSNIQY ITRFCNPSRL MTGEDGYYFT NLCCAVAFIE KLDAQSLNLS
QEDFDRFMTG QASPKKQESD SFSPDVCLGV KQMYKNLDLL SQLNERQERI VNEAKKLEKD
LIDWTDGVTK EVQDIVEKYP LEIEPKNQAL AAIDSENVEN DKLPPPLQPQ VYAG
//
