ID A0A1V4K552_PATFA Unreviewed; 478 AA.
AC A0A1V4K552;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Sodium channel protein type 8 subunit alpha {ECO:0008006|Google:ProtNLM};
GN ORFNames=AV530_009665 {ECO:0000313|EMBL:OPJ79576.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ79576.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ79576.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ79576.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ79576.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ79576.1}.
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DR EMBL; LSYS01004408; OPJ79576.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4K552; -.
DR STRING; 372326.A0A1V4K552; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR024583; Na_trans_cytopl.
DR InterPro; IPR043203; VGCC_Ca_Na.
DR PANTHER; PTHR10037:SF23; SODIUM CHANNEL PROTEIN TYPE 8 SUBUNIT ALPHA; 1.
DR PANTHER; PTHR10037; VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF11933; Na_trans_cytopl; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..221
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 344..470
FT /note="Voltage-gated Na+ ion channel cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF11933"
FT REGION 251..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 212..246
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 297..317
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 478 AA; 53595 MW; D13C240CCC54A75B CRC64;
MTPECFAPHA ARLSLIEDYR QNRRVHQYVA VPVPIEGLKT IVGALIQSVK KLSDVMILTV
FCLSVFALIG LQLFMGNLRN KCVIWPINVN ETFLDNGSKG FDWEEYTNNM SNFYIIPGAP
DPLLCGNSSD AGQCPEGYTC MKAGRNPNYG YTSFDTFSWA FLALFRLMTQ DFWENLYQLT
LRAAGKTYMI FFVLVIFVGS FYLVNLILAV VAMAYEEQNQ ATLEEAEQKE AEFKAMLEQL
KKQQEEQAAA MVTSAGTVSE DAVEDDGGGR MSRSSSEISK LSSKSAKERR NRRKKRKDKE
LSEGDEKCDN EKVFKSESED GMRRKAFRLP DNRLGRKFSI MNQSLLSIPG SPFLSRHNSK
SSIFSYKGRF CDPVSENEFA DDEHSTVEES EGRRDSLFIP IRGRDRRSSY SGYSGYSQGS
RSSRIFPNLR RNVKRNSTVD CNGVVSLIGG PPSSMPGGRL LPEVNTDTAA LRRLGVGG
//
