ID A0A1V4K652_PATFA Unreviewed; 538 AA.
AC A0A1V4K652;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Acid-sensing ion channel 4 {ECO:0000313|EMBL:OPJ79950.1};
GN Name=ASIC4 {ECO:0000313|EMBL:OPJ79950.1};
GN ORFNames=AV530_002378 {ECO:0000313|EMBL:OPJ79950.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ79950.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ79950.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ79950.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ79950.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC 1.A.6) family. {ECO:0000256|RuleBase:RU000679}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ79950.1}.
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DR EMBL; LSYS01004331; OPJ79950.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4K652; -.
DR STRING; 372326.A0A1V4K652; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR Gene3D; 1.10.287.770; YojJ-like; 1.
DR InterPro; IPR001873; ENaC.
DR PANTHER; PTHR11690:SF13; ACID-SENSING ION CHANNEL 4; 1.
DR PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR Pfam; PF00858; ASC; 1.
DR PRINTS; PR01078; AMINACHANNEL.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU000679};
KW Ion transport {ECO:0000256|RuleBase:RU000679};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW ECO:0000256|RuleBase:RU000679};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT TRANSMEM 68..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 15..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 538 AA; 60818 MW; A765E4DFB82929FF CRC64;
MPIEIVCKIK FAEEDEKQKE KEEGDKESLI EEPARPRSRD LATFASASTL HGLGHICRSG
QLGVRQTIWA FAFLVSLAFF LYQAAKSALL YLEHPHVMAL DEEAIREMVF PAITICNINR
YRHSALTDAD IFHLANMTGL PPKDRDGHKA TDLLYPDPDM ADIVNRTGHQ LDDMLKSCNF
SGENCSSRDF TVVYTRYGKC YTFNGDRRNP RVTRQGGMGN GLEIMLDIQQ EEYLPIWRET
NETSFEAGIR VQIHSQDEPP YIHQLGFGVS PGFQTFVSCQ EQRLTYLPQP WGNCRASVQG
EQMLPGYDTY SIAACRLQCE KEAVVRSCHC RMVHMPGNES ICSPNVYIEC ADHTLDAAVE
DSQERCSCPT PCNLTRYGKE ISMVRIPNKG SARYLARKYN KNETYIRENF LVLDIFFEAL
NYEAIEQKKA YDIAGLLGDI GGQMGLFIGA SILTILEILD YVYEVIRDKV SRVLRRSKPP
LKKPSGSIAT LGLEELKDQS PCATLGRHVE GAYNAGILPN HHHRHHYPHQ GVFEDFAC
//
