ID   A0A1V4K736_PATFA        Unreviewed;       685 AA.
AC   A0A1V4K736;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   22-FEB-2023, entry version 23.
DE   SubName: Full=Melanophilin isoform B {ECO:0000313|EMBL:OPJ80249.1};
GN   Name=MLPH {ECO:0000313|EMBL:OPJ80249.1};
GN   ORFNames=AV530_002610 {ECO:0000313|EMBL:OPJ80249.1};
OS   Patagioenas fasciata monilis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX   NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ80249.1, ECO:0000313|Proteomes:UP000190648};
RN   [1] {ECO:0000313|EMBL:OPJ80249.1, ECO:0000313|Proteomes:UP000190648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ80249.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:OPJ80249.1};
RA   Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA   Shapiro B.;
RT   "Band-tailed pigeon sequencing and assembly.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OPJ80249.1}.
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DR   EMBL; LSYS01004331; OPJ80249.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V4K736; -.
DR   STRING; 372326.A0A1V4K736; -.
DR   Proteomes; UP000190648; Unassembled WGS sequence.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   CDD; cd15752; FYVE_SlaC2-a; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR041282; FYVE_2.
DR   InterPro; IPR037442; Melanophilin_FYVE-rel_dom.
DR   InterPro; IPR006788; Myrip/Melanophilin.
DR   InterPro; IPR010911; Rab_BD.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR14555:SF1; MELANOPHILIN; 1.
DR   PANTHER; PTHR14555; MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED; 1.
DR   Pfam; PF02318; FYVE_2; 1.
DR   Pfam; PF04698; Rab_eff_C; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   PROSITE; PS50916; RABBD; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190648}.
FT   DOMAIN          4..124
FT                   /note="RabBD"
FT                   /evidence="ECO:0000259|PROSITE:PS50916"
FT   REGION          225..259
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          306..360
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          388..461
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          597..625
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          644..669
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          29..56
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          552..586
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        225..246
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..323
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        403..461
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        606..622
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   685 AA;  77011 MW;  BEAABF23997B2A8D CRC64;
     MGRKLDLSKL TDEEAKHVWE VVQRDFDLRK KEEERLEELK WKIDQESSKR EFLTNQSHLN
     ETHCVHCLQP FKFLLNSKRQ CLDCRFYTCK NCSRYNKKEQ GWVCDPCRLS RIVKIGSLEW
     YYEHVRSRFK RFGSAKVLQS LYGRLQPGQG LSSAFLGLHD RVYSLPDINS ECQLLTSGGA
     GDNSDDEDDV LRGAEAECYS RMRKTKRLLS VHPFDFELDS DYSSQSRRQS VQLSPAASSP
     DGFQSFPDFP NSAEDAPQKE SRIAEADLVF HHVLQEQGPG TSPPEQHFST EVRLTVNSRT
     RSLDRNAKLG SPWNEQPRST YSADMDTSDE DVKGVQFPAY PPHHVKRRNR TSSQENVSHS
     RNQIHELNKR MSAIECMLNR LEEKILVRSD ESPAPESQLD PDAEEEELKR KLEELASNIS
     DKEVSSEEEE CEEEKRVKKL EMSSSSDDMA RDARKRSSAK ALSEITAKVL RAINATEKAV
     CESLHGESQC NGGCALPTGQ LPSLGDGKEV AEAYRELEEN VYLTAGKTYR LEKTLKELEE
     GAQHSGTTDS ELSELEDKVA SAAAQVQKAE SEVSDIESRI AALSAAGLTV KSVEKARKKS
     SGQAACPDSP GPTSSSPGES SDDIGVMSGL QVFRRKFNIP LEISGPDDSF DRNSVYRGSL
     TQRNPNGKNR RVERLFAKPV MTHLS
//