ID A0A1V4K8S7_PATFA Unreviewed; 2838 AA.
AC A0A1V4K8S7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Dynein heavy chain 1, axonemal {ECO:0000313|EMBL:OPJ80795.1};
GN Name=DNAH1 {ECO:0000313|EMBL:OPJ80795.1};
GN ORFNames=AV530_004217 {ECO:0000313|EMBL:OPJ80795.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ80795.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ80795.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ80795.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ80795.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the dynein heavy chain family.
CC {ECO:0000256|ARBA:ARBA00008887}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ80795.1}.
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DR EMBL; LSYS01004144; OPJ80795.1; -; Genomic_DNA.
DR STRING; 372326.A0A1V4K8S7; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005930; C:axoneme; IEA:UniProt.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF28; DYNEINS HEAVY CHAIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648}.
FT DOMAIN 1455..1594
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1736..1893
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2100..2248
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 854..881
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2761..2788
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2838 AA; 325113 MW; 4E002D15FFB509E6 CRC64;
MYHSLVSQAN LEQHTPKVTT FQMPEDFASI LDKQRIGPTT EKLIESDFPA QSFQPKVQVA
FKVLPGQCPR RVEIERRRRL YLSFDIAQLL ASKGIDSNQL MPRHYDPDNM PTIAERADPI
FPIYLPLKIF DNKEYDCRTP EEWILLGLEP GSCDRKPVPG KALLPTDDVL GHEDPKNQKL
IYSWIDVGVL DYDKKTELYL VHKTDKNGLV RDEAGRPILN GGMTPEGRAP LLSCQYWVPR
VCLLFLAEDP RVFAQRVVDA HSLRKKTEAL LRYNLYVDCM PIDGLNSISE EWLECMKLLA
LQTPRLEKEE RVLDRMCPLE KEVRSDYERT MNKMIFDRVV SSKPQMFYYV TLPDKEEEKV
PEKGLVSIPD YPFAERRANF NFLSLLTRPE VILLLTQVQD ECNKAAAMSL FNSTLTEHVC
LEEFEQIQTQ TFTQVQVFLK DTWINTLKTA IKNNLRDSGK GLYDLEQDDW DLYQMSKLHK
LMTRIKFILQ DSVRYLVQNS LISFTQLLLD ACHDILNCSE DMEWGDDLIN SPYRPQRNPL
FKTDLVLDSR GVHFSPPVES FEKSLISLFN KGILVTHTVP QLEKYVLENM GITGTPLLNS
VDLHEPEVEE LRETVWSAIQ KARIPLQAYT KRYEKFLELN NNDIEYFLRE YEEQSPSAQE
VMTIVNTYLS EKENLQNTLP RSIVIGPFHV STEDVKRNLC KKYKALATSM LDLLAKNLHL
QVQNICDVYK AVSCKMHEKP NVIEELAELR EWMKGVPEQL AVQEELIHQV VEDYKVLEEF
LYKLSDKDFS DMWAARHWPH KIAMQTESIQ LQHLEDEEKF RKIQAIDQNV FQDKLEEMQL
IVYGFSVTVD TNQAHDLAKK AREVKKQLKE LQNLANVYNN RERIFGMKVT KYSTLSKMVK
DFQPYCDLWT TVSDWMQWHD SWMNDPLVEL EAEQLEKNVN ESSKTMQKCV RQFKDSPACQ
AVAMEFRDKI EDFKSYVPLI QGLNNPGMKS RHWEMLSEEI NMDIKPEPSL TVGHCLEMNL
LYHIETITKV AEIAGKEYAI ENALNKMESE WNSVFFIVEP YKDTGTFILK DTDEANQLTD
DHIVMVQSMS FSPFKKHFEE RMSTWENKLK ITQDVLEEWL NCQCSWLYLE PIFRSEDIKR
QLPLESQRYQ DMDTEWRNIM KNAKENPEVM SLCPDPVLLE NLRKCNNLLE LVQKGLSEYL
EMKRRAFPRF YFLSDDELLE ILSQTKDPTA VQPHLRKCFE NIAQLLFQED LQITHMYSAE
GEEVKLCVSI YPTDNVEEWL LEVEKSMKAS VRDHIERSIG VYPETARTTW VLQWPGQVVI
AGCQIFWTKE VSEALEAGDL SSRLYPQLTT QLGDLVALVR GHLSKMQRSV LSALIVIEVH
AKDVAAKLIE ENVTSMNDFE WISQLRYYWT KEDLYIRAVN AEFLYGYEYL GNSGRLVITP
LTDRCYLTLT GALHLKFGGA PAGPAGTGKT ETTKDLGKAL AIQTVVFNCS DQLDFMAMGK
FFKGLASAGA WACFDEFNRI DIEVLSVVAQ QITTIQKAQQ QRVDRFMFEG MEIPLVPSCA
VFITMNPGYA GRTELPDNLK ALFRPVAMMV PDYSMIAEIS LYSFGFNEAK VLAKKITTTF
KLLSEQLSSQ DHYDFGMRAV KTVISTAGNL KRENPTMDEE LICLRAIRDA NIPKFLQDDL
RLFRGIVSDL FPKIKEEPVD YGILEKAIRK SCIKENLKDV DGFVTKCIQL YETTVVRHGL
MLVGPTGSGK TKCYEVLAAA MTSLKGQPAA SGGNYEAVRY FVLNPKSITM GQLYGEFNLL
THEWTDGILS SLIRQGAAAT DTIKKWYMFD GPVDALWIEN MNTVLDDNKK LCLSSGEIIK
MTESMTMMFE VQDLAVASPA TVSRCGMVYL EPSILGLEPF IECWLQKIPS IIEPFSKQLA
SLFKRFLKDA IGFVRRFVKE ITASTDSNLT RSLLVLLECL FQPFIPSEGV RRIPQEKIAR
IGELIEPWFI FALIWSVGAT GDSQGRTAFS LWLREKMAKE KIQLLFPEDG LVYDYKLYDA
GLSSPEEDLD EEVIKEVCWE PWLDPTAKFT MVPDTNFCDI IVPTMNTVRM AHLLGLLLTN
RKPVLCIGPT GTGKTLTITD KLLKNLPPRY VTHFLMFSAR TSANQTQDLI DSKLDKRRKG
VFGPPVGRYF IFFIDDLNMP MLETYGAQPP IELLRQWMDH GGWYDRKQIG TFKKLVDINF
VCAMGPPGGG RNAVTPRFTR HFNYLSFTEM EDSSKKAIFS TILGCWMDGL LGERSHREPV
PEAVAIKDLN EPLVDATIGV YLTITSQLLP TPAKSHYTFN LRDLSKVFQG MLMAEPSKVE
NKLQLLRLWY HESCRVFCDR LVSKEDRTWF DNLMKSMMED FDTTFEEVVP SQPVLFGDFM
EPDAIVKQYE AIESQEKLKA VIEDYLEEYN QSNTLELKLV LFMDAIQHIC RISRILRQAP
GNALLLGVGG SGRQSLTRLA SHMADYECFQ IELSKNYGMT EWRDDVRKIM MKAGIQSLPK
TFLFVDTQIK NESFLEDINN LLNSGDIPNI YSLDDEDKIT TAMKPVVRDL GQQPTKANLM
AAYTRRVYSN MHMVLCMSPI GEVFRARLRQ FPSLVNCCTI DWFNKWPAEA LQSVASSVLQ
EIPHLGASTE DINGMVQVCV EIHQSVAKKC QVYLAELGRH NYVTPKSYLE FLSTFSSLIG
KKKQELKTAK KRMKGGLDKL LQTAEDVARM QEELESARPL LAQAAKDTEA TMEQLQVDTA
VAEKTRTAVQ AEEMKANAKA QAAQAIADDA QKDLAEALPA LDAALASLRN LKKNDVTESW
HEESPVYARL PMPTHKVH
//
