GenomeNet

Database: UniProt
Entry: A0A1V4KF46_PATFA
LinkDB: A0A1V4KF46_PATFA
Original site: A0A1V4KF46_PATFA 
ID   A0A1V4KF46_PATFA        Unreviewed;      4844 AA.
AC   A0A1V4KF46;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   07-NOV-2018, entry version 8.
DE   SubName: Full=Ryanodine receptor 3 isoform A {ECO:0000313|EMBL:OPJ83096.1};
GN   Name=RYR3 {ECO:0000313|EMBL:OPJ83096.1};
GN   ORFNames=AV530_010517 {ECO:0000313|EMBL:OPJ83096.1};
OS   Patagioenas fasciata monilis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae;
OC   Patagioenas.
OX   NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ83096.1, ECO:0000313|Proteomes:UP000190648};
RN   [1] {ECO:0000313|EMBL:OPJ83096.1, ECO:0000313|Proteomes:UP000190648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ83096.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:OPJ83096.1};
RA   Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA   Shapiro B.;
RT   "Band-tailed pigeon sequencing and assembly.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OPJ83096.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; LSYS01003385; OPJ83096.1; -; Genomic_DNA.
DR   Proteomes; UP000190648; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF49899; SSF49899; 3.
DR   SUPFAM; SSF82109; SSF82109; 1.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50222; EF_HAND_2; 1.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000190648};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:OPJ83096.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4159   4183       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4386   4406       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4450   4472       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4645   4666       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4721   4744       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      100    155       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      162    207       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      215    269       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      275    341       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      343    400       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      585    796       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1012   1208       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1254   1468       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     3903   3931       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   COILED      459    479       {ECO:0000256|SAM:Coils}.
FT   COILED     3225   3245       {ECO:0000256|SAM:Coils}.
FT   COILED     4306   4326       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   4844 AA;  549586 MW;  D878E9085F5EF1A8 CRC64;
     MAEGGEGGED EIQFLRTDDE VVLQCVASIH KEQRKFCLAA EGLGNRLCFL EPTSEAKYVP
     PDLCICNFVL EQSLSVRALQ EMLASTGDNA SEGAAQGGGH RTLLYGHAIL LRHSFSEMYL
     TCLTSSRSQT DKLAFDVGLR ENAAGEACWW TIHPASKQRS EGEKVRIGDD LILVSVSSER
     YLHLSMSNGS IHVDASFMQT LWNVHPTCSG SNITEGYLLG GHVVRFFHGH DECLTIPSTD
     QNDSQHKKVL YETGGAGIRA RSLWRVEPLR ISWSGSNIRW GQPFRLRHIT TGRYLALSED
     EGLAMVDREK SDTKSTAFCF RASKEMKEKQ DSNVKRDIEG MGVPEIKYGD SVCFVQHVAS
     ALWLTYKAQD AKSARLGPLK RKVILHQEGH MDDGLTLQRC QHEESQAARI IRNTTSLFSQ
     FISGNNRTLS PSALPVEEMA QTLQDLITYF QLPKEDLDHE DKQNKLRSLK NRQNLFKEEG
     MLALVLNCID RLNDYNSAAH FAGVARDENG TAWKEILNLL YKLLAALIRG NRNNCTQFSS
     NLDWLISKLD RLESSSGILE VLHCILIESP EALNTISEEH IKSIISLLDK HGRNYKVLDV
     LCSLCVCNGV AVRANQNLIC DNLLPRRDLL LQTRLINDVT SIRPNIFLGV AEGSAQYKKW
     YFELIIDQVE PFLTAEPTHL RVGWASTSGY APYPGGGEGW GGNGVGDDLY SYGFDGLHLW
     SGRVPRAVAS VNQHLLASDD VVSCCLDLGV PSISFRINGQ PVQGMFENFS TEGFFFPVVS
     LSAGVKVRFL LGGRHGEFKF LPPTGYAPCY EALLPKEKMK LEPVKEYKRD SEGVRDLLGT
     TQFLSQASFI PCPIDTSQIA LPFHLEKIRD KLAENIHELW GMNKIELGWT YGKIRDDNKR
     HHPCLVEFSK LPETEKNYNL QMSTETLKTL LALGCHIVHA HPAAEEDLKK VKLPKNYMMS
     NGYKPAPLDL SEVKLLPSQE FLVDKLAENA HNVWAKDRIK QGWTYGIQQD LKNKRNPRLV
     PYALLDERTK KSNRDSLREA VRTFAGYGYS VEPPDQEIAD QTVEKVSIDK IRFFRVEQSY
     AVKSGKWYFE FEAVTGGDMR VGWARPGCRP DIELGADDQA FVFEGSKGQR WHQGSGFFGR
     SWQPGDVVGC MINLDDKSII FTLNGELLIT SKGSELAFAD FGIESGFVPI CALGLSQIGR
     MNLGMDASTF KYYTMCGLQE GFEPFAVNMN RDVAMWFSKR LPTFVNVPKN HPHIEICRID
     GTIESPPRLK VTHKTFGTQN SNSDMIYCRL SMPIEFRSSF NFSTGVENAS SDVFQKRKHS
     QEIAALSTTY FYSLRIFAGQ DPSSVWVGWV TPDYHFYSEN FDLNKNCTVT VTLGDERGRV
     HESVKRSNCY MVWGGDVIAN SQRSGRSNVD LEIGCFVDLA TGMLSFTANG KELGACYQVE
     PNTKLFPATF VQPTSTNLIQ FELGKLKNTM PLSAAIFKSE ERNPVPQCPP RLDVQTITPV
     LWSRMPNSFL KVETERVSER HGWVVQCLEP LQMMALHIPE ENRCVDILEL CEQEDLMMFH
     YHTLKLYCSV SALGNTRVAY ALCSHVDVSQ LFYTIDNQYL PGLLRSGFYD LLISIHLEYA
     KKAKLMMNNE FIIPVTDETR TIKLYPDETK KHGLPGVGLS TCLKPDFNFS TPCFILASEE
     RQTSSPEIPL DILKSKAISM LTEAVQCSGA HIRDPVGGQV AFQFVPVLKL IATLLIMGVF
     DDDDVKQVLL LIDPNVFGDH KEETEERMEK EEVTQVEEKA VEAGEKAIKE TKAPAKGLLQ
     TRLPESVKLQ XXXXLNYFCD CELQHRVEAI VSFADCYVSK LQYNQKYRYN ELMQALNMSA
     ALTAKKTKEF RSPPQEQINM LLNFQLGEDC PCPEEIRDEL YEFHDDLLIH CGIPLEEEEE
     EEEDSSLTGK LRSLMYKIKG PPKAEKVEPK EEEEKSPTTL KELISQTMVR WSQEDHIQDP
     ELVRIMYTLL RRQYDSIGEL LQALRKAYTI SAASVKDTIN LLAALGQIRS LLSVRMGKEE
     ELLMINGLGD IMNNKVFYQH PNLMRVLGMH ETVMDVMVNV LGGGDKSQQI VFPKMVASCC
     RFLCYFCRIS RQNQKAMFEH LSYLLENSSV GLAFPSMRGS TPLDVAAASV MDNNELALAL
     EEPDLDKVVT YLAGCGLQSC PVLLAKGYPD IGWNPIEGER YLSFLRFAVF VNSESVEENA
     SVVVKLLIRR PECFGPDLRG EGGNGLLAAM QEAIRISENP ARDLPSQAYK REGDDEEEEE
     EEEIVHMGNA IMSFYSALID LLGRCAPEMH LIQSGKGEAI RIRSILRSLV PTEDLVGIIS
     IPLKLSTVNK DGTVNEPDMS ANFCPDHKAP MVLFLDRVYG IKDQSFLLHL LEVGFLPDLR
     ASASLDTVSL STTEAALALN RYICSAVFPL LKRCAPLFSG TEHHASLVDS MLHTIYRLSK
     GRSLTKAQRD TIEDCLLAVC HHLRPSMLQQ LLRRLVFDVP LLNEYCKMPL KLLTNHYEQC
     WKYYCLPSGM GSCGIATEEE LHLTEKLFWG IFDSLSHKKY DPELFRMALP CLSAIAGALP
     PDYLDTRIRS TLEKQTSVDP EGNFDPKPVN TANLVLPEKL EYIVSKYAEH SHDKWAFDKT
     NSGWKYGVSL DENMKTHPLI RPFKTLTEKE KEIYRWPARE SLKTMLAMGW SLERTKEGEA
     LIHQRENEKL RSISQSSQGN GYSPMPLDLS NVVLSRELQG MVEVMAENYH NIWAKKKKME
     LESKGGGSHP LLVPYDTLTA KEKSRDREKA QELFKFLQVN GIIISRGLND MELDASSMEK
     RFAFKFLKKI LKYVDSAQEF IAHLEAIVTS GKTEKSPHDQ EIKFFAKVLL PLVDQYFTNH
     CLYFLSSPTK TLSSSGYASN KEKEMVASLF CKLAALVRHR ISLFGSDSAT MVNCLHILAQ
     SLDTRTVMKS GSELVKAGLR AFFENAAEDL EKTSENLKLG KFTHSRTQMK GVSQNINYTT
     VALLPILTSI FEHISQHQFG IDLLLGDVQV SCYRILCSLY SLGTGKNIYV ERQRPALGEC
     LASLAAAIPV AFLEPSLNHY NPLSVFNTKS ARERAILGMP DTVEEMCPEI PQLDGLIKEI
     NDLAESGARY TEMPHVIEVI LPMLCNYLSY WWERGSESVP QSAGPCCTMI TSEHLSIVLG
     NILKIINNNL GIDEASWMKR IAVYAQPIIS KARPDLLKTH FIPTLEKLKK KAVKIVMEEE
     QLKADSKSDT QEAELLILDE FAVLCRDLYA FYPMLIRYVD NNRANWLKKP DADSDELFRM
     VAEVFILWCK SHNFKREEQN FVIQNEINNL AFLTGDTKSK MSKSGGQDQE RKKTKRRGDL
     YSIQTSLIVA ALKKMLPIGL NMCTPGDQEL ISLAKSRYSH RDTDDEVKEH LRNNLHLQEK
     SDDPAVKWQL NLYKDILKND EPTDPERNVE RVQRISAALY HLEQVEQPLR SKKAVWHKLL
     SKQRKRAVVA CFRMAPLYNL PRHRSINLFL HGYQNYWIET EEYSFEEKLV QDLATPPKID
     EEEEEETEKK HPDPLHQIIL YFSRTALTER SKLEDDPLYI AYSAMMAKEK EMEKQRTLYQ
     QARLHDRGAA EMVLQMISAS QGHTGPMVIE TLKLGIAILN GGNTVVQQKM LDYLKEKKDA
     GFFQSLSGLM QSCSVLDLNA FERQNKAEGL GMVTEEGTRE KVLQRDEFTR DLFRFLQLLC
     EGHNNDFQNY LRTQMGNTTT VNIIISTVDY LLRLQESISD FYWYYSGKDV IDESGQRNFS
     KALAVTKQIF NSLTEYIQGP CIGNQQSLAH SRLWDAVVGF LHVFANMQMK LSQDSAQIEL
     LKELLDLLKD MVVMLLSLLE GNVVNGTIGK QMVDTLVESS SNVEMILKFF DMFLKLKDLT
     NSDAFKEYDP DGKGIISKKE FQKSMEAQKQ YIQSEIEFLL SCAEADENDM FNYVDFVERF
     HEPAKDIGFN VAVLLTNLSE HMPNDSRLQS LLEPAESVLN YFEPYLGRIE IMGGAKKIER
     VYFEISESSR MQWEKPQVKE SKRQFIFDVV NEGGEQEKME LFVNFCEDTI FEMQLASQIS
     ETDSSERPEE DEEEESCYVV DIGDDEEEEK SLESASAFAM ACVAVKKNVA NFLKMVTVKN
     LKKQYRKVRK MTVKEMVKVF FSFFWLLFVG MFQLFFTIVW GIFQILWSTV FGGGLVEGAK
     NIKVTKILGD MPDPTQFGIH DDVMEAEKAE GAEHGIRDDL AQSVKGEKGE ADIISDIFGI
     PTKKEGGSKH AHDAGLGDIA EILGIDIQST LENTVQKKKG LQISEIAKEA ETKRKAEAEK
     ADMEDGEKQD KAKEVQSEQL EEGKMKKKKR RHGQKVEKPE AVMANFFKAL EVYQTKMLHY
     LARNFYNLRF LALFVAFAIN FILLFYKVTE EPLDEVEEDS NLWNSFDEEE EEEGMVFFVL
     EESTGYMAPA LRALAVIHTI ISFVCVIGYY CLKVPLVVFK REKEVARKLE FDGLYITEQP
     SEDDIKGQWD RLVINTPSFP NNYWDKFVKR KVINKYGDLY GAERIAELLG LDKSALDFSP
     VEESEPEEAS LVSWLSSIDT KYHIWKLGVV FTDNSFLYLV WYTTMSILGH YNNFFFAAHL
     LDIAMGFKTL RTILSSVTHN GKQLVLTVGL LAVVVYLYTV VAFNFFRKFY NKSEDEDEPD
     MKCDDMMTCY LFHMYVGVRA GGGIGDEIED PAGDPYEMYR IVFDITFFFF VIVILLAIIQ
     GLIIDAFGEL RDQQEQVKED METKCFICGI GNDYFDTTPH GFETHTLQEH NLANYLFFLM
     YLINKDETEH TGQESFVWKM YQERCWDFFP AGDCFRKQYE DQLG
//
DBGET integrated database retrieval system