ID A0A1V4KJB8_PATFA Unreviewed; 1864 AA.
AC A0A1V4KJB8;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform B {ECO:0000313|EMBL:OPJ84509.1};
GN Name=GBF1 {ECO:0000313|EMBL:OPJ84509.1};
GN ORFNames=AV530_015908 {ECO:0000313|EMBL:OPJ84509.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ84509.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ84509.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ84509.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ84509.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ84509.1}.
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DR EMBL; LSYS01003057; OPJ84509.1; -; Genomic_DNA.
DR STRING; 372326.A0A1V4KJB8; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1631..1651
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 696..886
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 221..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 621..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1294..1335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1437..1486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1730..1754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1767..1809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..341
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 621..642
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1294..1322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1448..1463
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1776..1804
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1864 AA; 208426 MW; FA793C1C2597F37D CRC64;
MRGIVRMVDK NIYIVQGEIN VVVGAIKRNA RWSTHTHLDE ERDPLLHSFS LLKEVLNNIT
ELSEIEPNVF LRPFLEVIRS EDTTGPITGL ALTSVNKFLS YALIDPSHEG TAEGMENMAD
AVTHARFVGT DHASDEVVLM KILQVLRTLL LTPVGAHLTN ESVCEIMQSC FRICFEMRLS
ELLRKSAEHT LVDMVQLLFT RLPQFKEEPK SYIGTNMKKL KMRAGGMSES SKWKKQKRSP
RPPRHVTKVS PGTEQPPANA SNITASGVTF IDAPSPSSSG SSENVSSAVS PATDSGLELS
SQTTSKEDLT DLDQVTSLGL NTGMPSNEAK VTENNNQPEL QNEGLREEKN QSASVESIPE
VLEECTSIAE HSDSASVHDM DYVNPRGVRF TQSSQKEGAT LVPYGLPCIR ELFRFLISLT
NPHDRHNSEV MIHMGLQLLT VALESAPIAN CQSLLGLVKE ELCRHLFQLL SVERLNLYAA
SLRVCFLLFE SMREHLKFQL EMYIKKLMEI ITVENPKMPY EMKEMALEAI VQLWRIPSFV
TELYINYDCD YYCANLFEEL TKLLSKNAFP VSGQLYTVHL LSLEALLTVI DSTEAHCQAK
VLSNMNQQEK ELVKSNLETL NSTRETSNNN ERVLSEGKSS SAVSEPAGVC PPSSGCLMAD
QMKDGCMELE GGSEAAEKSI PRKPTRFSCI LPSPQELMQI KNKKKLLITG TEQFNQKPKK
GIQFLQEKNL LATPIDNNEV ARWLRENPRL DKKMIGEFVS DRKNIDLLES FVGTFSFQGL
RLDEALRLYL EAFRLPGEAP VIHRLLEAFT EHWRKSNGSP FANSDACFAL AYAVIMLNTD
QHNHNVRKQN VPMTLEEFRK NLKGVNGGKD FEQDILEDMY HAIKNDEIVM PEEQTGLVKE
NYIWNVLLHR GATDEGIFLH VPPGSYDHDL FTMTWGPTIA ALSYVFDKSL EETIIQKAIS
GFRKCAMISA HYGLSDVFDN LIISLCKFTA LNSESIENLP TVFGSNPKAH IAAKTVFHLA
HRHGDILREG WKNIMEAMLQ LFRAELLPKA MVEVEDFVDP NGKIYLQREE TPSNRGESTV
LSFVSWLTLS GTEQSGMRGP STETQEAKRT ALECIKQCDP EKLITESKFL QLESLQELMK
ALISVTPDEE TYDEEDAAFC LEMLLRIVLE NRDRVTCVWQ TVRDHLYHLC VHAMEFCFLV
ERAVVGLLRL AIRLLRREEI SAQVLLSLRI LLMMKPNVLS RVSHEVAYGL HELLKTNAAN
IHSGDDWYTL FTLLECIGSG VKPPAALQVT ARADNDTGAQ SDSEVSSSCH PSDMSLDRGY
TSDSEVYTDH GKPGKMHRSV TDVDVMNSGW LVVGKDDIDT SRSTAGLSRL GPSPLVNQYS
LTVGLDLGPH DTKSLMKCVE SLSFIVRDAA HVTPENFELC VKTIRIFVEA SLNGGYKSQE
KRGKSHRYDS KSSRLKKKPK ESSTRRSRVL TQHQAHTHSD EDEDETIPAS YHTVSLQVSQ
DLLDLMHTLH TRAATIYSSW AEEHRHLETV GRKIEADSRT LWSNCWCPLL QGIAWLCCDA
RRQVRMQALT YLQRALLVHD LQALDALEWE SCFNKVLFPL LTKLLENISP ADVGGMEETR
MRASTLLSKV FLQHLSPLLS LTTFAALWLT ILDFMDKYMH AGSSDLLLEA IPESLKNMLL
VMDTAGIFHS ADSRTGYSDL WEITWERIDC FLPRLRDELF KQTVIQDPVP SIPMEQQHQK
SIVPPSPVGD VRPATHLAPL EKPCEVGASE SERAAAPASP TISTSASPSF PASAPTKTSP
VTDIPPTTAQ PPLILQPLAS PLQVGVPPMT LPIILNPALI EATSPVPLLA TPRSTDPMTT
SEVN
//
