ID   A0A1V4KM87_PATFA        Unreviewed;       756 AA.
AC   A0A1V4KM87;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Leucine-rich repeat and calponin-like proteiny domain-containing protein 3 isoform A {ECO:0000313|EMBL:OPJ85582.1};
GN   Name=LRCH3 {ECO:0000313|EMBL:OPJ85582.1};
GN   ORFNames=AV530_001785 {ECO:0000313|EMBL:OPJ85582.1};
OS   Patagioenas fasciata monilis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX   NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ85582.1, ECO:0000313|Proteomes:UP000190648};
RN   [1] {ECO:0000313|EMBL:OPJ85582.1, ECO:0000313|Proteomes:UP000190648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ85582.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:OPJ85582.1};
RA   Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA   Shapiro B.;
RT   "Band-tailed pigeon sequencing and assembly.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OPJ85582.1}.
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DR   EMBL; LSYS01002834; OPJ85582.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V4KM87; -.
DR   Proteomes; UP000190648; Unassembled WGS sequence.
DR   CDD; cd21272; CH_LRCH3; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR48051; -; 1.
DR   PANTHER; PTHR48051:SF44; LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 3; 1.
DR   Pfam; PF00307; CH; 1.
DR   Pfam; PF13855; LRR_8; 2.
DR   SMART; SM00033; CH; 1.
DR   SMART; SM00364; LRR_BAC; 4.
DR   SMART; SM00369; LRR_TYP; 5.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS50021; CH; 1.
DR   PROSITE; PS51450; LRR; 2.
PE   4: Predicted;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          630..743
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          394..468
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          517..586
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          602..633
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        404..451
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        517..568
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        602..622
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   756 AA;  85128 MW;  1787F030BD6E1676 CRC64;
     MPAGSAAACP PPPGPSGPGS WSRSLDRALE DAAASGTLSL SGRKLRDYPR ASAANHDLSD
     TTQADFSRNR LSELPAEACH FVSLESLNLY QNCIRYIPEA VLNLQSLTFL NISRNQLSTL
     PVHLCNLPLK VLIASNNKLV SIPEEIGQLR QLTELDVSCN EIQTIPPQIG NLESLRDLNV
     RRNNLVRLPE ELAELPLIRL DFSCNKITTI PVCYRNLRHL QTIMLENNPL QSPPAQICIK
     GKIHIFKYLN IEACKIAPDL PDYDRRPMGF GSCHEELYSS RPYGALDSGF NSVDSGDKRW
     SGNEPTDEFS DLPLRVAEIT KEQRLRRESQ YQENRGSTVV TNGGVEHDLD QIDYIDSCAT
     EEEEEEMRQP KCADSESLSS QFVAYIDQRR ISNESSPVKP VSVREFQRTE DTKRYLHHNR
     DTDELRRPET LNLMQDREQH RVLRSYVDRT ERPPPDSPYF LSLSSHHSQV TDPELHRRHV
     ERTRQEAQLA AFRYEEERMR TKQIQREAVL DFVKQKASLS PQKQSPLDSE CPFPSRRSQH
     TDDSALLVSD DRSTISAGSP TTQTVHLSPP YPGHAAPPSY RNPSQRPESF LFRAAVRDEA
     NKAVTSSSTR ALSPATDSAD PRARQNSKQR EEELELIEQL RKNIESRLKV SLPSDLGAAL
     TDGVVLCHLA NHVRPRSVPS IHVPSPAVPK LTMAKCRRNV ENFLEACRRI GVPQEQLCLP
     LHILEEKGLT QVAVTVQALL ELAPPKQQQL HHLSAV
//