ID A0A1V4KSY5_PATFA Unreviewed; 1330 AA.
AC A0A1V4KSY5;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Caskin-1 isoform A {ECO:0000313|EMBL:OPJ87476.1};
GN Name=CASKIN1 {ECO:0000313|EMBL:OPJ87476.1};
GN ORFNames=AV530_000945 {ECO:0000313|EMBL:OPJ87476.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ87476.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ87476.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ87476.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ87476.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ87476.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LSYS01001700; OPJ87476.1; -; Genomic_DNA.
DR STRING; 372326.A0A1V4KSY5; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd09497; SAM_caskin1_2_repeat1; 1.
DR CDD; cd09498; SAM_caskin1_2_repeat2; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 2.
DR InterPro; IPR033635; ANKS1/Caskin.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR032232; Caskin1-CID.
DR InterPro; IPR035497; Caskin1/2_SAM_1.
DR InterPro; IPR035498; Caskin1/2_SAM_2.
DR InterPro; IPR032117; Caskin_C.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24174; ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR24174:SF11; CASKIN-1; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF16632; Caskin-tail; 1.
DR Pfam; PF16600; Caskin1-CID; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00454; SAM; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 6.
DR PROSITE; PS50088; ANK_REPEAT; 6.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000190648};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT REPEAT 43..75
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 76..108
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 109..141
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 142..166
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 183..215
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 215..247
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 276..342
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 554..617
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 623..687
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 375..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 454..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 703..898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 961..1030
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1043..1265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..392
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..807
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..987
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1058..1075
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1107..1162
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1173..1193
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1198..1239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1330 AA; 140389 MW; E1042B4D459433B5 CRC64;
MGTPVCLMLA SGAAVPSLRG GVPLSAELLG SAKKVNVNFQ DTDGFSALHH AALNGNTELI
SLLLEAQAAV DIKDNKGMRP LHYAAWQGKK EPMKMVLKAG SSVNIPSDEG QIPLHLAAQH
GHYDVSEMLL QHQSNPCIMD NSGKTPLDLA CEFGRVGVVQ LLLNSNMCAA LLEPKPGDTT
DPNGTSPLHL AAKNGHIDII RLLLQAGIDI NRQTKAGTAL HEAALCGKTD VVRLLLDSGI
NAHVRNTYNQ TALDIVNQFT TSQASKEIKQ MLRDASAALQ VRAIKDYCNN YDLTSLNVKA
GDVITVLEQH ADGRWKGCIH DNRTGNDRVG YFPSSLVEAI SKRTGSWETV TIPQQYQKIP
LPAYGAAVLN GDASSHPFHS LPPPPPPPPH SHQTLFSSFG YRRLSPSSAD EPRDAQGSRG
ADMSPSHLSP SQGGPAAPAP TEEIWVLRKP FAGGDRSSLG STGSVASARS SGSGQSAGSG
AHALHASSEG VKLLATVLSQ KASAQESAVG DGPAKAQDIP AGSSRSQSVA SSPYAPPPPA
EPQLKKMEPP SEGKSSEAVY QWLCKFQLQL YAPNFINAGY DITTISRMTP EDLTAIGVTK
PGHRKKIASE INNLNIPEWL PEYKPANLAL WLSMIGLSQY YKVLVENGYE NIDFITDITW
EDLQEIGITK LGHQKKLMLA VKKLAELQRA ELGKYEPGTL KRKAAACPED SELSSELQVA
MTGEAPEEPP EKSQEYLAEG AGEGPPAPPK EGRPPRHGHP VKRASVPPVP GKPRQPFPPS
AGHLTPPQTP VKPTPQLLPP GERPASPRSL PQSPTHREGP YATVQRRVGR SHSKKGPPPP
PPKRSSSAIS SAGMAEDFPK EGEGEAAPTG PLTTEGESRR EQRRASDLGG SVDTGSAGSV
RSIAAMLEMS SIGGGARALA LQKPHGASGP AKHKEAIGLD GEVVNRRRTI SGPVTGLVAA
ARRERADSVR SDVGADSPGE RLRVERGGSP DAIPFAEDGN LTIKQRPRPL GPARGEAGEG
LSPAHRHGDL AKVEASATLK RRIRARQSQQ DGVRFVLTES DTVKRRPKAK EKEPALEPAL
LAVYQNGTGT VKRRPASELS GVEPPATLPP AARPDGPDYV PPPAEPKKPF KPPVSPKPVL
TQPPQKVPGP PASVPKKVPI PSPGSPEVKR VHGTPPPVSP KPVPPPTAPK PPKPHATIQS
VSAGSTPTPS PARQLGAGTA KPSSTPPSLC SSPAKPLSPG AQPQQVPVKP PRSAIAGPSV
DTTGPELAQQ KLEETSASLA AALQAVEEKI KQEDSQTADS AVESKSTVSI LDDIGSMFDD
LADQLDAMLE
//
