ID   A0A1V4KTL3_PATFA        Unreviewed;      1233 AA.
AC   A0A1V4KTL3;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=MHC class II transactivator isoform A {ECO:0000313|EMBL:OPJ87768.1};
GN   Name=CIITA {ECO:0000313|EMBL:OPJ87768.1};
GN   ORFNames=AV530_001170 {ECO:0000313|EMBL:OPJ87768.1};
OS   Patagioenas fasciata monilis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX   NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ87768.1, ECO:0000313|Proteomes:UP000190648};
RN   [1] {ECO:0000313|EMBL:OPJ87768.1, ECO:0000313|Proteomes:UP000190648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ87768.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:OPJ87768.1};
RA   Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA   Shapiro B.;
RT   "Band-tailed pigeon sequencing and assembly.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OPJ87768.1}.
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DR   EMBL; LSYS01001700; OPJ87768.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V4KTL3; -.
DR   Proteomes; UP000190648; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR025875; Leu-rich_rpt_4.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR008095; MHC_II_transact.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47189; MHC CLASS II TRANSACTIVATOR; 1.
DR   PANTHER; PTHR47189:SF1; MHC CLASS II TRANSACTIVATOR; 1.
DR   Pfam; PF12799; LRR_4; 1.
DR   Pfam; PF13516; LRR_6; 2.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   PRINTS; PR01719; MHCIIACTVATR.
DR   SMART; SM00368; LRR_RI; 4.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000190648}.
FT   DOMAIN          505..640
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   1233 AA;  138309 MW;  3976921185A252AC CRC64;
     MEAMFRFCSD VLLTSSDAAM NLFKEILPRV RKILSAATAS DEHALLNLML KEDVISKEYH
     QALLHEKDRE DLARKISLTF VEKWDLYLTA LVPLCCLNLC GSKPQNVTDN EPTGSKYISD
     SKGQIMDSAL LSENGCLDLL HSDIDPLHLY TVLDPKSSGN EDDVFSVDPE VDANNNDQVN
     NMDFPYALEN GENGDELYLC SNTRDAYARI AELAEYVLKD HQEKLIEDAF AGNLIWDEIT
     AENTEKFTDI KMQKCHKRPF LGSAESCSEA SEPKYKKMVE GPAVPAGNGS FLAMPPHSHP
     AGSTSLTNQY MSFSVPAANV LERSFVIPGS STPLIPECLP VSTEGSQEDT DFADPPQQIL
     NFVLESGTSD VIIYPVLTSS METLVSPSFP ASLCGLEMFK EVRVPLIPSE EPPKRPKPVE
     AFRASLMEYF RDVCKSVAME REVALDHLFI DGTLVQNQTE TKTGKNSIKT MEKELVTCSL
     QGKEKAALTR SQIFQIPGGK DLETKVIVVL GKAGMGKSIL VQKICQDWSS GELSQFEFVF
     WFDCKQISLP EKRYSLKDLL LDFFVKPQEG SKEIFEYILQ NPAKVLLAFD GFEGLHDHEN
     FPRCSASQPE KALFSVKELL SGLIQKKILN GCTLLLTARP KDKVYQFVSK VDKTIELVGF
     SPQQRELYIT KYFEGLRYCD NALNLIKERE YLFSHCYSPV MCRFVCFLCE TVLETGDKNL
     PSTLTTVFLK FVQQKMMPMQ TDVTALQNQE SLATLARLAW HLGEKHQSAL KSDLLPSKEV
     KEFALKHGFF LPFAFPNHSD AGEEEFGNTF SDFVIQNFLG ALHLMLAEEI KDKSLTKYLS
     FPSKKKKPYN WLDLVPRFLA GLLFLQDDPC FCCLSNKDVK QSTKKQKTLL KYIKRLQINE
     LCPERLLELF HCIYETQSSY LFQHVALRLK PDLSFLGIVL TPPDVHVLHS VLKRSRKEFS
     LDLRNSSIDI QGLKDLVGLT NVASFRASLS DTVRLWKSLE QTKDYELLRA STEKFVLDPF
     KAKTMKDISD LSDLVEIQEK MINCVQDASG CSSYEIPAIK NLRKLEFALG PVCGLQGFLK
     LVEILAAFPS LQHLDLDALS ENGIGDEGAK SLSEVFPTLK SLETLNLSQN KITDVGAEKL
     ATALPSLLSL KTLSLYNNSI CDFGAENLAK VLPAMASLRV LEVQYNKITG VGAQQLTDSL
     RKCPHIKNLV MWNPTIPYGV LEHLQQLDSR ISV
//