ID A0A1V4L197_PATFA Unreviewed; 1035 AA.
AC A0A1V4L197;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Ras GTPase-activating-like protein IQGAP2 isoform B {ECO:0000313|EMBL:OPJ90490.1};
GN Name=IQGAP2 {ECO:0000313|EMBL:OPJ90490.1};
GN ORFNames=AV530_008672 {ECO:0000313|EMBL:OPJ90490.1};
OS Patagioenas fasciata monilis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Patagioenas.
OX NCBI_TaxID=372326 {ECO:0000313|EMBL:OPJ90490.1, ECO:0000313|Proteomes:UP000190648};
RN [1] {ECO:0000313|EMBL:OPJ90490.1, ECO:0000313|Proteomes:UP000190648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BTP2013 {ECO:0000313|EMBL:OPJ90490.1};
RC TISSUE=Blood {ECO:0000313|EMBL:OPJ90490.1};
RA Soares A.E., Novak B.J., Rice E.S., O'Connell B., Chang D., Weber S.,
RA Shapiro B.;
RT "Band-tailed pigeon sequencing and assembly.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPJ90490.1}.
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DR EMBL; LSYS01000242; OPJ90490.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V4L197; -.
DR Proteomes; UP000190648; Unassembled WGS sequence.
DR CDD; cd05131; RasGAP_IQGAP2; 1.
DR Gene3D; 1.20.5.190; -; 2.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR000593; RasGAP_C.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR PANTHER; PTHR14149:SF12; RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP2; 1.
DR Pfam; PF00612; IQ; 4.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF03836; RasGAP_C; 1.
DR SMART; SM00015; IQ; 4.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF143885; RGC domain-like; 1.
DR PROSITE; PS50096; IQ; 4.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000190648}.
FT DOMAIN 375..608
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
SQ SEQUENCE 1035 AA; 119085 MW; 8B025313E46E9440 CRC64;
MRFIESQDES VLLWLDEIQN GINDANNNIK EAVILAVGTS MINKSLEKGD LEPILMILQS
KFGLRVVPEC AEAYFRNLSE AKQLKTREDS NESPWIKLVM KNMYDYYYNV ETEEGTCVAP
EGVVPKTSWL TGEEIQSVVG QVTADYNREQ LWLANENLIV QLQARARGFL VRKKYQERKA
YLRNQEPSTI KIQAFWKGFK QRKSYVDRLK VFQGNVGAII KIQSWVKMWL ARRAYRKRLQ
YFKDHNAEIV KIQAFLRANK ARDDYRTLIG AENPPLTQLE KDLNLMDIKI GLLVKNRITL
QDVVLHSKKL NKKSKSQLEE MVMVDKQGIK GLSKERRKKL EAYQHLFYLL QTNPTYLAKL
IFQMPQNKST KFMDTVIFTL YNYASNQREE YLLLKLFKTA LEEEINSKVD QIQDIVTGNP
TVIKMVVSFN RGARGQNTLR QLLAPVVKEI MDDKSLIINT SPVDVYKSWV NQLEMQTGEA
SKLPYDVTTE QALTHTEVVN KLESSIQSLR AVTDKVLASI FSSLNMMPYG MRYIAKVLKS
SLHEKFPDAT EDELLKIVGN LLYYRYMNPA IVAPDGFDII DMTAGGQIHP DQRRNLGCVA
KVLQHAASNK LFEGESEHLS SMNTYLSQTY QKFRNFFQAA CDVPEPEEKF NIDEYSDMVT
LSKPVIYISI EEIINTHSLL LEHQDAIATE PNDLLNELLE GLGPVPDVES FLGEGAVDPN
DPNRESTLSQ LAKTEISLSL TSKYELREGE DQDLKSLMIK TKRLIVDVIR TQPGDTLLEI
LETPATAQQE SEHSKLAEKR AILDSKTPEK MKHSKSIFED GQLPIEQKKR KIQRNLRTLE
QAGLVSSATK YQEIINEIAK DIRNQRRYRH HRKAELVKLQ QTLNALNSKT AFYEEQINYY
NTYIKTCLDN LTRKNSRRSI KLDGKEEVKG SKKLKQTSLK YTAARLHEKG VILEIEDLQT
NQFKNVMFDI TPGEEVGDFE IKAKFLGVEM EKVQLHFQDL LQMQYEGVAV MKMFDKAKVN
VNLLIFLLNK KFYGK
//
