ID   A0A1V6M3K2_9BACT        Unreviewed;       343 AA.
AC   A0A1V6M3K2;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Uroporphyrinogen decarboxylase (URO-D) domain-containing protein {ECO:0000259|Pfam:PF01208};
GN   ORFNames=BIY37_00705 {ECO:0000313|EMBL:OQD46957.1};
OS   Candidatus Brocadia sapporoensis.
OC   Bacteria; Planctomycetota; Candidatus Brocadiia; Candidatus Brocadiales;
OC   Candidatus Brocadiaceae; Brocadia.
OX   NCBI_TaxID=392547 {ECO:0000313|EMBL:OQD46957.1, ECO:0000313|Proteomes:UP000242219};
RN   [1] {ECO:0000313|EMBL:OQD46957.1, ECO:0000313|Proteomes:UP000242219}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=40 {ECO:0000313|EMBL:OQD46957.1,
RC   ECO:0000313|Proteomes:UP000242219};
RX   PubMed=27932661;
RA   Ali M., Haroon M.F., Narita Y., Zhang L., Rangel Shaw D., Okabe S.,
RA   Saikaly P.E.;
RT   "Draft Genome Sequence of the Anaerobic Ammonium-Oxidizing Bacterium
RT   'Candidatus Brocadia sp. 40'.";
RL   Genome Announc. 4:e01377-16(2016).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQD46957.1}.
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DR   EMBL; MJUW02000017; OQD46957.1; -; Genomic_DNA.
DR   RefSeq; WP_070065923.1; NZ_MJUW02000017.1.
DR   AlphaFoldDB; A0A1V6M3K2; -.
DR   Proteomes; UP000242219; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:InterPro.
DR   GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.210; -; 1.
DR   InterPro; IPR006360; Mtase_MtaA_CmuA.
DR   InterPro; IPR038071; UROD/MetE-like_sf.
DR   InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR   NCBIfam; TIGR01463; mtaA_cmuA; 1.
DR   PANTHER; PTHR47099; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   PANTHER; PTHR47099:SF1; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   Pfam; PF01208; URO-D; 1.
DR   SUPFAM; SSF51726; UROD/MetE-like; 1.
PE   4: Predicted;
KW   Methanogenesis {ECO:0000256|ARBA:ARBA00022994};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242219}.
FT   DOMAIN          2..336
FT                   /note="Uroporphyrinogen decarboxylase (URO-D)"
FT                   /evidence="ECO:0000259|Pfam:PF01208"
SQ   SEQUENCE   343 AA;  37257 MW;  CB34324F5B2151FC CRC64;
     MTEKERLLKI LHDVKVDRPP VIAPGGMMTM ASKEVMEMTN CRWPAVHRDA EKMAALSIAM
     HDEAGIENLG IPFCMTVEAE ALGGEVEDGD EVTEPHIIKY PLESVEEWRN LKALNPHKDG
     RLPAILTCTS LLSKGRPDIP VIGNLVGPLS LASSLIDATL LFRALRREPE EVHRMLGFLN
     DNSIRYGQAL ISNGADLIVI SDPSATGEIL GPRMFDEFAL PYLNAMIAGI HMLGKPVIVH
     ICGNVAPVQE LLKKLDSECI SVDSVVNIKE MRNAIPGKKL MGNISAILLQ NGPVDKIQTV
     SKNLLDFGVD ILAPACGLSA KTPVRHIRAM TDTAKTTSAK LQA
//