ID A0A1V6MK00_9ACTN Unreviewed; 891 AA.
AC A0A1V6MK00;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Polyketide synthase {ECO:0000313|EMBL:OQD52800.1};
GN ORFNames=BM536_032450 {ECO:0000313|EMBL:OQD52800.1};
OS Streptomyces phaeoluteigriseus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=114686 {ECO:0000313|EMBL:OQD52800.1, ECO:0000313|Proteomes:UP000184286};
RN [1] {ECO:0000313|Proteomes:UP000184286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41896 {ECO:0000313|Proteomes:UP000184286};
RA Schniete J.K., Salih T., Algora Gallardo L., Martinez Fernandez S.,
RA Herron P.R.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OQD52800.1, ECO:0000313|Proteomes:UP000184286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41896 {ECO:0000313|EMBL:OQD52800.1,
RC ECO:0000313|Proteomes:UP000184286};
RA Salih T.S., Algora Gallardo L., Melo Santos T., Filgueira Martinez S.,
RA Herron P.R.;
RT "Draft genome sequence of Streptomyces phaeoluteigriseus type strain
RT DSM41896.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD52800.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MPOH02000019; OQD52800.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6MK00; -.
DR STRING; 114686.BM536_032450; -.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000184286; Unassembled WGS sequence.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR CDD; cd05235; SDR_e1; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR013120; Far_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR010080; Thioester_reductase-like_dom.
DR NCBIfam; TIGR01746; Thioester-redct; 1.
DR PANTHER; PTHR44845:SF6; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR44845; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07993; NAD_binding_4; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 102..178
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 57..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 217..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..691
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 891 AA; 95186 MW; F832FB98C15D05A8 CRC64;
MRDMNEDAAA NAGQRTDAGQ RTDAGQRADA GRATAEEIER GGGGLGVSEL LALVMTADPA
GPGPASGDSA PTPRSDATAP AVDATAPAVD ATGPAVDAAD PAFDQDGLAD AIAVAAGRHL
PQGHLDADAD FFDAGGSSVH AVELAAELER DLGVELDLDD VFADARPSSL ARRWLERGGR
AAPLPAPRTA DAEKLPAPAP AVLPTSAPAA AQAILSVRSP RSAQPAPVTT LPLPDLGDDP
HSTARREDLD QILADLALAD RLPFLRSPEP LPPRRILLTG ATGFLGSHML LDLLRHSDAH
VYCLVRGADE EAATARLAEQ LRTYRLPWNA EVRRRVTVLP GDIRRPRLGL SEELWHTLAH
ELDSVVGVAA AVDFLRGYQS LRAGNVLGAL TLAELAATGR PKPLHHISSI AVFNEVGISS
MGEDDPFAHV DRLVAGYDQS KWAAETALRR ARDHGLIVSA LRPGGIGGHT KTGAYNPQDL
SSGLISAFGR FRTVPAFRYL NAAPVDWVSR VAVAVVCEPD AWGFDYNLTG VPNTLDDVVR
DMAFGGMHVR VEDWDEWRTD TLARLQAQPV PELAFLTRVL QSPTALKLCE ATLRGPAASA
ERTDALVEAL GLTPAARYDA QAQLKTFEKL AGDGLARLPR KEDQPYLWFA ETTEGRVHRA
GGTESTAGTE STAGTAGTES TAGTASMAGA ESTADTADHD DSPGSPCSMA LTLSIASMYQ
LVKERRIDVS GEITCPAAHA EPLTVVHGDI WVRPEEGIPQ QHGLKHPLLR YRLRLHDADG
RPWWLEGHKY ARARRDLWRQ TRALTIELGR EGEPAAFTGE VVVPADSYVR DQIDGIKVAP
HLAGREKRAA KLTWLAWFGL EMGRGLAGPF ARAAADLLDL RRTPNPTERH R
//
