ID A0A1V6MUW0_9ACTN Unreviewed; 956 AA.
AC A0A1V6MUW0;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=AfsR family transcriptional regulator {ECO:0000313|EMBL:OQD56145.1};
GN ORFNames=BM536_015145 {ECO:0000313|EMBL:OQD56145.1};
OS Streptomyces phaeoluteigriseus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=114686 {ECO:0000313|EMBL:OQD56145.1, ECO:0000313|Proteomes:UP000184286};
RN [1] {ECO:0000313|Proteomes:UP000184286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41896 {ECO:0000313|Proteomes:UP000184286};
RA Schniete J.K., Salih T., Algora Gallardo L., Martinez Fernandez S.,
RA Herron P.R.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OQD56145.1, ECO:0000313|Proteomes:UP000184286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 41896 {ECO:0000313|EMBL:OQD56145.1,
RC ECO:0000313|Proteomes:UP000184286};
RA Salih T.S., Algora Gallardo L., Melo Santos T., Filgueira Martinez S.,
RA Herron P.R.;
RT "Draft genome sequence of Streptomyces phaeoluteigriseus type strain
RT DSM41896.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD56145.1}.
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DR EMBL; MPOH02000011; OQD56145.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6MUW0; -.
DR STRING; 114686.BM536_015145; -.
DR Proteomes; UP000184286; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 4.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..81
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..81
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 237..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 956 AA; 102266 MW; 21AA50812794F3EC CRC64;
MRARRGEQPL ATGSPQQRAL LAALLLREGR TATAAELIDA LWGEEPPSQA LAAVRTYASR
LRKVLDPGVL VSESGGYAVR GLREGALDLA VAQDWAAEAE KAKGAGALGR ARELLNRALG
LWDGEALAGV PGPYAEAQRV RLEEWRLGLL ESRLDMDLEQ GCHAEAVSEL TALTAAYPLR
ERLRELLMLA LYRSGRQAEA LAVYADTRRL LAEELGVDPR PGLRELQRRI LQADPDLAEP
SAQQAEPSPA PVRPAQLPAT VPDFTGRSSF VTELSEVLAG ASGDGGRVMA VSALAGIGGV
GKTTLAVHVA HRARPAFPDG QLYVDLQGAG SRSAEPETVL GAFLRALGTA DSAIPDSLEE
RAALYRSMLD GRRVLVLLDN AKDAAQVRPL LPGTEGCAAL VTSRVRMVDL AGAHLVDLDV
MSPEEALALF TRIVGEERVA SERKAALDVV AACGFLPLAI RIAASRLASR RTWTVSVLAA
KLADERRRLD ELQAGDLAVK ATFELGYGQL EPAQARAFRL LGLADGPDMS LAAAAAVLDL
APEETEDLLE SLVDTSLLES AAPGRYRFHD LVRLYARACA ERDESSPGER AAAMSRLLDF
YLATTAQVYA IEHPRDRLVD DLEATSYPGL RFTEGAAALD WLYTEAGPLL ACVRQAAGTA
RLRRAVDLLW AAKDLTESGA NSHQYETAAR ATCDATRAMG DERAEGRART VLSDVLLVSG
RIRQAEDEAK VAMALASAAH DATAVSWVAN NRGLICLHQS RFGDGKVFFD QALEGLRASG
NRPFEATALG NLSRAYLGMG NTDKAVEIAR RGLAAHSEIG RSVRLANSHF ALGVALTQAG
LHAEALTEFS DALRIFNEHR QRLWEGVTNF RIAQVHLAAR RPAQAAQHAE LALTLGCIGG
DRMRGNVLTL LGRALAELAQ VDRARACWQD ALTLYEQSGA PESDVVRGLL TCASAG
//
