ID A0A1V6NZI9_PENDC Unreviewed; 926 AA.
AC A0A1V6NZI9;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PENDEC_c028G02770 {ECO:0000313|EMBL:OQD69987.1};
OS Penicillium decumbens.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=69771 {ECO:0000313|EMBL:OQD69987.1, ECO:0000313|Proteomes:UP000191522};
RN [1] {ECO:0000313|Proteomes:UP000191522}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 11843 {ECO:0000313|Proteomes:UP000191522};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD69987.1}.
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DR EMBL; MDYL01000028; OQD69987.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6NZI9; -.
DR STRING; 69771.A0A1V6NZI9; -.
DR OMA; METHQDG; -.
DR OrthoDB; 9867at2759; -.
DR Proteomes; UP000191522; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0007127; P:meiosis I; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd03281; ABC_MSH5_euk; 1.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF20; MUTS PROTEIN HOMOLOG 5; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000191522}.
FT DOMAIN 307..640
FT /note="DNA mismatch repair protein MutS core"
FT /evidence="ECO:0000259|SMART:SM00533"
FT DOMAIN 670..866
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|SMART:SM00534"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 467..494
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 29..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 926 AA; 102366 MW; 685AB29B628AEFE6 CRC64;
MRSSQKRKHS PAVSRSHAPL VTPRTAGSRG RASIISSGSF HPPASAAQQS QAPFPTETQL
GGEEHERSSD DDDAGHIIAA IDMKDYGTVG CSYYSREEEK LYLMGDSKSG EMETINALIL
QIKPTVILTP PRVDLLNVAG QNLAQGNDSS SYLPYQVDVR PSQEFTYSNA ESRLVALDVS
SSHEERLRFF VPQSGLNGPE EEANPENMGF TLHEGRLLHI SSSVDMENPV TLGCAGALLS
YLQRRRATTS VGPLETNLSR VRYLEMFSLQ DTMWIGSNTL LSLQIIQPES HPNMFNQGPG
KKSASGKEGL SVYGLYRRFA YTPQGRAKLK QMFFHPSLSL DTIRERHDFI TMFSRPGNSA
ALEKMIKGLK HIKNLRPVMI NLHKGISTGS AKITGFKATV WASLLAFAFY SIDIHDALRE
ISGAEVLARR TKALQIFEAA QLHRVGRMIQ EIVDIDNSEE QGRTVVKQGL DRELDKMKDR
YDGLNNLLKN VALEIATTIP EELDIDVNVI YFPQLGFNIA ISLNGSGDPA YSGAVGDWEL
VFTTETRAYF KDFRMRELDE RLGDIYGLIC EKEIEIVYDL AQRVLQYENV LIEASDVCGE
MDSLLALTQA ASFYKLTRPR MVSENVIKIK GGRHILQELT VSSYVPNDTL LAGGKENLED
KIHSSVDQVS SMLLLTGPNY SGKSVYMKQV ALIVYLAQIG SFVPADMAEL GITDKILTKI
NTQESVSQIQ STFMSDLQQI SLCLKQVTGR NLVLIDEFGK GTSESDGIGL ACGILEHLLT
IEDVPKVIAA THFHEIFENG FLAPRPRLQL GHMEVKVCEE FQEVVDQVTY LYNFRPGRSS
KSFGTICAAI NGIGPAIVSR ANEIAILAAR GENLVAACAM LSSEEMQTLQ HANTLARNFL
KIDFSLEGRS SHDMKAILED LFQPGA
//
