ID A0A1V6PIB3_PENDC Unreviewed; 885 AA.
AC A0A1V6PIB3;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PENDEC_c004G06162 {ECO:0000313|EMBL:OQD76603.1};
OS Penicillium decumbens.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=69771 {ECO:0000313|EMBL:OQD76603.1, ECO:0000313|Proteomes:UP000191522};
RN [1] {ECO:0000313|Proteomes:UP000191522}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 11843 {ECO:0000313|Proteomes:UP000191522};
RX PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA Frisvad J.C., Workman M., Nielsen J.;
RT "Global analysis of biosynthetic gene clusters reveals vast potential of
RT secondary metabolite production in Penicillium species.";
RL Nat. Microbiol. 2:17044-17044(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQD76603.1}.
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DR EMBL; MDYL01000004; OQD76603.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1V6PIB3; -.
DR STRING; 69771.A0A1V6PIB3; -.
DR OMA; RKTWIYE; -.
DR OrthoDB; 1328399at2759; -.
DR Proteomes; UP000191522; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd04399; RhoGAP_fRGD2; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 2.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR23065:SF17; RHO-GTPASE-ACTIVATING PROTEIN RGD2; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Reference proteome {ECO:0000313|Proteomes:UP000191522}.
FT DOMAIN 2..433
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 212..296
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 467..665
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 675..885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 729..746
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..802
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 847..866
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 885 AA; 98597 MW; 646927EC4D8971C1 CRC64;
MPGFSDSFWT PDYATGLGVL YGKLQQGVVE NRQILTMASM RADAEEQYGL RMGEIAPSVD
RMTGAGFGKD DGASVRKAYE GVRTEMIEAS RNHQKIANNI RELVVAPFRR WSDQHDYRVQ
ASHDNLQTRI KEHSKQVELV KKLRSVYFNK CRVLEDLEEE NKLAFQDPDM SPKIMPTPKI
VLPAEEEQEE EPVELGDRIF PPEEIKKILA HMLHNIRIGE AKVPIIGTYQ NTSTGADIVE
YVQTYMDATN LAQAERIGQD LVDNGFLRLV GNMGSVFANS SKMNYQWRSK VFKLTGIPEK
KKPLMRVTSV ASSEDGNVSD SPISSVSEML AGWNPLNNPH PNETPSEKLR REALEADERY
KNAVRRLDQI RCRLEEDVIE NLRFMEQCEL DRLKAIKAVV LDFSGAISNV IPNLQSTVDH
MMLYQETIQP LGDLRYLLEN YRTGGFVPRV QAYENYYGSV EEQNFGVDLE ARARVDRKRV
PILVTTLLTY LDNRYPELEG DEARRAIWLH NPPLAITHQL RSVLNNSKVD YREVLPKYQI
PVVASVLKLY LLELPDSLVS SQVYEIVKTI YSTTAHETTE EGRIKVLQST LGQLRLVNIA
TLDAIMTHFT RLIDLTSADE QYIASLAQIM SPCVLRPRTE SSLTMDERHS YRLIRDLFAH
KDAIFNELKR QSSALGISTS SRPRAISTDE SNRRAAMEAR QRAIVNRTRA TSPTGRQRHR
RDRSSGASET GRFPINVSSP ADRRTTRGTS LDVPAEGSPT GAEHPTVDTQ ITDGSISNGA
STESPASLPA SASSSEGSVS PPPPAETASD GSPTPTPTPA AISTEFEKRA SIPRSAGARY
TRKPGLGSLS SFPTSAGSVG TDSKRSSIAE SEPKGVTLED KPMDD
//
