ID   A0A1V6PJE6_PENDC        Unreviewed;       413 AA.
AC   A0A1V6PJE6;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Saccharopine dehydrogenase NADP binding domain-containing protein {ECO:0000259|Pfam:PF03435};
GN   ORFNames=PENDEC_c004G01135 {ECO:0000313|EMBL:OQD76646.1};
OS   Penicillium decumbens.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=69771 {ECO:0000313|EMBL:OQD76646.1, ECO:0000313|Proteomes:UP000191522};
RN   [1] {ECO:0000313|Proteomes:UP000191522}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBT 11843 {ECO:0000313|Proteomes:UP000191522};
RX   PubMed=28368369; DOI=10.1038/nmicrobiol.2017.44;
RA   Nielsen J.C., Grijseels S., Prigent S., Ji B., Dainat J., Nielsen K.F.,
RA   Frisvad J.C., Workman M., Nielsen J.;
RT   "Global analysis of biosynthetic gene clusters reveals vast potential of
RT   secondary metabolite production in Penicillium species.";
RL   Nat. Microbiol. 2:17044-17044(2017).
CC   -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00038048}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQD76646.1}.
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DR   EMBL; MDYL01000004; OQD76646.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1V6PJE6; -.
DR   OMA; CEYRAIA; -.
DR   OrthoDB; 5479972at2759; -.
DR   Proteomes; UP000191522; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000191522};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        275..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          9..138
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
SQ   SEQUENCE   413 AA;  45303 MW;  040A8C216CDBEADD CRC64;
     MPNGQYDLVL LGPTGYTGRL CAQHIVKNHP TSLKWAIAGR SATKMDPIAQ ELKELNPDRV
     QPDVLVVQLN LEELNELAQK TKIIINCVGP YYLYSTPVVE ACATNGTHYL DVTGETPWIK
     QLIEKYHETA KSNGAIIMPS VGVESAPADM LAWALVKRIR SDYSSGTRCI ESCIKEMKSA
     GPSGGTLATI LGIFDSLPLS QLLKSADTFS LAASAPPKDI PGDSILQKLL GVRSIRDLGA
     VTTSPNGFAD MTIVHRSSTL MPEFYGKRFF FHQFLYVRNT LIGALVHIGL IFSLVLLMIP
     PVRWVLRKFI FAPGKGPSIQ ASQNDRLEYH AVATADQSDP SPIRVFGTLT YEGSMYVLTG
     LLVSEAAMVI LREEEKVKKT SRCGIVTPAT LGQDYIDRLS NVGVNIETRV FQY
//